1niq

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[[Image:1niq.jpg|left|200px]]
 
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{{Structure
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==Solution Structure of the HOO-Bm bound BLMT, Transposon Tn5-encoding Bleomycin-binding Protein==
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|PDB= 1niq |SIZE=350|CAPTION= <scene name='initialview01'>1niq</scene>
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<StructureSection load='1niq' size='340' side='right'caption='[[1niq]]' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=BLM:BLEOMYCIN+A2'>BLM</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>
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<table><tr><td colspan='2'>[[1niq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NIQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NIQ FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 1 model</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BLM:BLEOMYCIN+A2'>BLM</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1niq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1niq OCA], [https://pdbe.org/1niq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1niq RCSB], [https://www.ebi.ac.uk/pdbsum/1niq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1niq ProSAT]</span></td></tr>
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|RELATEDENTRY=[[1mh6|1MH6]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1niq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1niq OCA], [http://www.ebi.ac.uk/pdbsum/1niq PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1niq RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/BLE_KLEPN BLE_KLEPN] Binding protein with a strong affinity to the bleomycin family of antibiotics. Binds to CL990; an antimitotic-antibiotic compound.
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== Evolutionary Conservation ==
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'''Solution Structure of the HOO-Bm bound BLMT, Transposon Tn5-encoding Bleomycin-binding Protein'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ni/1niq_consurf.spt"</scriptWhenChecked>
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1NIQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NIQ OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1niq ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Klebsiella pneumoniae]]
[[Category: Klebsiella pneumoniae]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Sugiyama, M.]]
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[[Category: Sugiyama M]]
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[[Category: bleomycin complex]]
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[[Category: blmt]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:30:57 2008''
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Current revision

Solution Structure of the HOO-Bm bound BLMT, Transposon Tn5-encoding Bleomycin-binding Protein

PDB ID 1niq

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