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4m84

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==Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1455==
==Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1455==
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<StructureSection load='4m84' size='340' side='right' caption='[[4m84]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='4m84' size='340' side='right'caption='[[4m84]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4m84]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxgo Toxgo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M84 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M84 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4m84]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M84 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M84 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=21E:5-AMINO-1-TERT-BUTYL-3-(QUINOLIN-2-YL)-1H-PYRAZOLE-4-CARBOXAMIDE'>21E</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.998&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AAG53993, CDPK1, TGGT1_059880, TGVEG_042030 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5811 TOXGO])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=21E:5-AMINO-1-TERT-BUTYL-3-(QUINOLIN-2-YL)-1H-PYRAZOLE-4-CARBOXAMIDE'>21E</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium/calmodulin-dependent_protein_kinase Calcium/calmodulin-dependent protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.17 2.7.11.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m84 OCA], [https://pdbe.org/4m84 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m84 RCSB], [https://www.ebi.ac.uk/pdbsum/4m84 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m84 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m84 OCA], [http://pdbe.org/4m84 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4m84 RCSB], [http://www.ebi.ac.uk/pdbsum/4m84 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4m84 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9BJF5_TOXGO Q9BJF5_TOXGO]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Calcium/calmodulin-dependent protein kinase]]
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[[Category: Large Structures]]
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[[Category: Toxgo]]
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[[Category: Toxoplasma gondii]]
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[[Category: Merritt, E A]]
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[[Category: Merritt EA]]
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[[Category: Atp-binding]]
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[[Category: Bumped kinase inhibitor]]
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[[Category: Calcium-binding]]
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[[Category: Serine/threonine protein kinase]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]
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Current revision

Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1455

PDB ID 4m84

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