This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4c18

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:01, 20 December 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==The structure of the Tsi2 dimer with a disulfide bond==
==The structure of the Tsi2 dimer with a disulfide bond==
-
<StructureSection load='4c18' size='340' side='right' caption='[[4c18]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
+
<StructureSection load='4c18' size='340' side='right'caption='[[4c18]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4c18]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C18 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C18 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4c18]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C18 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C18 FirstGlance]. <br>
-
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4c15|4c15]]</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.49&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c18 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c18 OCA], [http://pdbe.org/4c18 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4c18 RCSB], [http://www.ebi.ac.uk/pdbsum/4c18 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4c18 ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c18 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c18 OCA], [https://pdbe.org/4c18 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c18 RCSB], [https://www.ebi.ac.uk/pdbsum/4c18 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c18 ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TSI2_PSEAE TSI2_PSEAE] Immunity protein that plays a role in preventing early activation of toxin Tse2. Binds to a large surface of Tse2 and thereby occludes the active site to specifically inhibits Tse2.<ref>PMID:22310046</ref> <ref>PMID:22511866</ref> <ref>PMID:26749446</ref>
 +
== References ==
 +
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Boraston, A B]]
+
[[Category: Large Structures]]
-
[[Category: Nano, F E]]
+
[[Category: Pseudomonas aeruginosa]]
-
[[Category: Robb, C S]]
+
[[Category: Boraston AB]]
-
[[Category: Anti-toxin]]
+
[[Category: Nano FE]]
-
[[Category: Immunity protein]]
+
[[Category: Robb CS]]
-
[[Category: T6ss]]
+
-
[[Category: Toxin]]
+

Current revision

The structure of the Tsi2 dimer with a disulfide bond

PDB ID 4c18

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools