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4gme
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==Crystal structure of mannonate dehydratase (target EFI-502209) from caulobacter crescentus cb15 complexed with magnesium and d-mannonate== | ==Crystal structure of mannonate dehydratase (target EFI-502209) from caulobacter crescentus cb15 complexed with magnesium and d-mannonate== | ||
| - | <StructureSection load='4gme' size='340' side='right' caption='[[4gme]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='4gme' size='340' side='right'caption='[[4gme]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4gme]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4gme]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caulobacter_vibrioides_CB15 Caulobacter vibrioides CB15]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GME OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GME FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=CS2:D-MANNONIC+ACID'>CS2</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=CS2:D-MANNONIC+ACID'>CS2</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gme FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gme OCA], [https://pdbe.org/4gme PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gme RCSB], [https://www.ebi.ac.uk/pdbsum/4gme PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gme ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/MAND2_CAUVC MAND2_CAUVC] Catalyzes the dehydration of D-mannonate. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref> |
| + | |||
| + | ==See Also== | ||
| + | *[[Mandelate racemase/muconate lactonizing enzyme 3D structures|Mandelate racemase/muconate lactonizing enzyme 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Caulobacter vibrioides CB15]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Almo SC]] |
| - | [[Category: | + | [[Category: Bhosle R]] |
| - | [[Category: | + | [[Category: Chowdhury S]] |
| - | [[Category: Evans | + | [[Category: Evans B]] |
| - | [[Category: Gerlt | + | [[Category: Gerlt JA]] |
| - | + | [[Category: Hammonds J]] | |
| - | [[Category: Hammonds | + | [[Category: Hillerich B]] |
| - | [[Category: Hillerich | + | [[Category: Imker HJ]] |
| - | [[Category: Imker | + | [[Category: Patskovsky Y]] |
| - | [[Category: Patskovsky | + | [[Category: Scott Glenn A]] |
| - | [[Category: | + | [[Category: Seidel RD]] |
| - | [[Category: | + | [[Category: Toro R]] |
| - | [[Category: | + | [[Category: Washington E]] |
| - | [[Category: | + | [[Category: Zencheck WD]] |
| - | [[Category: | + | |
| - | + | ||
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Current revision
Crystal structure of mannonate dehydratase (target EFI-502209) from caulobacter crescentus cb15 complexed with magnesium and d-mannonate
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Categories: Caulobacter vibrioides CB15 | Large Structures | Almo SC | Bhosle R | Chowdhury S | Evans B | Gerlt JA | Hammonds J | Hillerich B | Imker HJ | Patskovsky Y | Scott Glenn A | Seidel RD | Toro R | Washington E | Zencheck WD
