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4h0n
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==Crystal structure of Spodoptera frugiperda DNMT2 E260A/E261A/K263A mutant== | ==Crystal structure of Spodoptera frugiperda DNMT2 E260A/E261A/K263A mutant== | ||
| - | <StructureSection load='4h0n' size='340' side='right' caption='[[4h0n]], [[Resolution|resolution]] 2.71Å' scene=''> | + | <StructureSection load='4h0n' size='340' side='right'caption='[[4h0n]], [[Resolution|resolution]] 2.71Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4h0n]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4h0n]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Spodoptera_frugiperda Spodoptera frugiperda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H0N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H0N FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.712Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h0n OCA], [https://pdbe.org/4h0n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h0n RCSB], [https://www.ebi.ac.uk/pdbsum/4h0n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h0n ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TRDMT_SPOFR TRDMT_SPOFR] Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp) (By similarity). Also has DNA (cytosine-5)-methyltransferase activity (PubMed:23103599). Shows affinity for both tRNA(Asp) and DNA substrates (PubMed:23103599).[UniProtKB:O14717]<ref>PMID:23103599</ref> | ||
==See Also== | ==See Also== | ||
| - | *[[DNA methyltransferase|DNA methyltransferase]] | + | *[[DNA methyltransferase 3D structures|DNA methyltransferase 3D structures]] |
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Ding | + | [[Category: Spodoptera frugiperda]] |
| - | [[Category: Du | + | [[Category: Ding J]] |
| - | [[Category: Li | + | [[Category: Du J]] |
| - | [[Category: Yang | + | [[Category: Li S]] |
| - | [[Category: Yin | + | [[Category: Yang H]] |
| - | [[Category: Zhong | + | [[Category: Yin J]] |
| - | + | [[Category: Zhong J]] | |
| - | + | ||
Current revision
Crystal structure of Spodoptera frugiperda DNMT2 E260A/E261A/K263A mutant
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Categories: Large Structures | Spodoptera frugiperda | Ding J | Du J | Li S | Yang H | Yin J | Zhong J
