3twa

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==Crystal structure of gluconate dehydratase (TARGET EFI-501679) from Salmonella enterica subsp. enterica serovar Enteritidis str. P125109 complexed with magnesium and glycerol==
==Crystal structure of gluconate dehydratase (TARGET EFI-501679) from Salmonella enterica subsp. enterica serovar Enteritidis str. P125109 complexed with magnesium and glycerol==
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<StructureSection load='3twa' size='340' side='right' caption='[[3twa]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='3twa' size='340' side='right'caption='[[3twa]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3twa]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Salep Salep]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TWA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3twa]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Enteritidis_str._P125109 Salmonella enterica subsp. enterica serovar Enteritidis str. P125109]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TWA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TWA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3tw9|3tw9]], [[3twb|3twb]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SEN1436 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=550537 SALEP])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3twa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3twa OCA], [https://pdbe.org/3twa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3twa RCSB], [https://www.ebi.ac.uk/pdbsum/3twa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3twa ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3twa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3twa OCA], [http://pdbe.org/3twa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3twa RCSB], [http://www.ebi.ac.uk/pdbsum/3twa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3twa ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DGD_SALEP DGD_SALEP]] Has low D-gluconate dehydratase activity (in vitro), suggesting that it has no significant role in D-gluconate degradation in vivo. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref>
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[https://www.uniprot.org/uniprot/DGD_SALEP DGD_SALEP] Has low D-gluconate dehydratase activity (in vitro), suggesting that it has no significant role in D-gluconate degradation in vivo. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Salep]]
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[[Category: Large Structures]]
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[[Category: Almo, S C]]
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[[Category: Salmonella enterica subsp. enterica serovar Enteritidis str. P125109]]
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[[Category: Bhosle, R]]
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[[Category: Almo SC]]
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[[Category: Chowdhury, S]]
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[[Category: Bhosle R]]
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[[Category: EFI, Enzyme Function Initiative]]
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[[Category: Chowdhury S]]
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[[Category: Evans, B]]
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[[Category: Evans B]]
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[[Category: Gerlt, J A]]
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[[Category: Gerlt JA]]
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[[Category: Glenn, A Scott]]
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[[Category: Hammonds J]]
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[[Category: Hammonds, J]]
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[[Category: Hillerich B]]
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[[Category: Hillerich, B]]
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[[Category: Imker HJ]]
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[[Category: Imker, H J]]
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[[Category: Patskovsky Y]]
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[[Category: Patskovsky, Y]]
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[[Category: Scott Glenn A]]
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[[Category: Seidel, R D]]
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[[Category: Seidel RD]]
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[[Category: Toro, R]]
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[[Category: Toro R]]
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[[Category: Washington, E]]
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[[Category: Washington E]]
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[[Category: Zencheck, W D]]
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[[Category: Zencheck WD]]
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[[Category: Enolase]]
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[[Category: Lyase]]
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[[Category: Magnesium binding site]]
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Current revision

Crystal structure of gluconate dehydratase (TARGET EFI-501679) from Salmonella enterica subsp. enterica serovar Enteritidis str. P125109 complexed with magnesium and glycerol

PDB ID 3twa

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