4hfx
From Proteopedia
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==Crystal structure of a transcription elongation factor B polypeptide 3 from Homo sapiens, Northeast Structural Genomics consortium target id HR4748B.== | ==Crystal structure of a transcription elongation factor B polypeptide 3 from Homo sapiens, Northeast Structural Genomics consortium target id HR4748B.== | ||
| - | <StructureSection load='4hfx' size='340' side='right' caption='[[4hfx]], [[Resolution|resolution]] 2.54Å' scene=''> | + | <StructureSection load='4hfx' size='340' side='right'caption='[[4hfx]], [[Resolution|resolution]] 2.54Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4hfx]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4hfx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HFX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HFX FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.54Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hfx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hfx OCA], [https://pdbe.org/4hfx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hfx RCSB], [https://www.ebi.ac.uk/pdbsum/4hfx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hfx ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/ELOA1_HUMAN ELOA1_HUMAN] SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). |
==See Also== | ==See Also== | ||
| - | *[[ | + | *[[Elongation factor 3D structures|Elongation factor 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Acton TB]] |
| - | [[Category: | + | [[Category: Ciccosanti C]] |
| - | [[Category: | + | [[Category: Everett JK]] |
| - | [[Category: | + | [[Category: Hunt JF]] |
| - | [[Category: | + | [[Category: Montelione GT]] |
| - | [[Category: Sahdev | + | [[Category: Sahdev S]] |
| - | [[Category: Seetharaman | + | [[Category: Seetharaman J]] |
| - | [[Category: Su | + | [[Category: Su M]] |
| - | [[Category: Tong | + | [[Category: Tong L]] |
| - | [[Category: Xiao | + | [[Category: Xiao R]] |
| - | + | ||
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| - | + | ||
Current revision
Crystal structure of a transcription elongation factor B polypeptide 3 from Homo sapiens, Northeast Structural Genomics consortium target id HR4748B.
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Categories: Homo sapiens | Large Structures | Acton TB | Ciccosanti C | Everett JK | Hunt JF | Montelione GT | Sahdev S | Seetharaman J | Su M | Tong L | Xiao R
