We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

4a0g

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:17, 20 December 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Structure of bifunctional DAPA aminotransferase-DTB synthetase from Arabidopsis thaliana in its apo form.==
==Structure of bifunctional DAPA aminotransferase-DTB synthetase from Arabidopsis thaliana in its apo form.==
-
<StructureSection load='4a0g' size='340' side='right' caption='[[4a0g]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
+
<StructureSection load='4a0g' size='340' side='right'caption='[[4a0g]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4a0g]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A0G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A0G FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4a0g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A0G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A0G FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.502&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4a0f|4a0f]], [[4a0h|4a0h]], [[4a0r|4a0r]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a0g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a0g OCA], [http://pdbe.org/4a0g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4a0g RCSB], [http://www.ebi.ac.uk/pdbsum/4a0g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4a0g ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a0g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a0g OCA], [https://pdbe.org/4a0g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a0g RCSB], [https://www.ebi.ac.uk/pdbsum/4a0g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a0g ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/BIODA_ARATH BIODA_ARATH]] Bifunctional enzyme that catalyzes two different reactions involved in the biotin biosynthesis. Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring. Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor.
+
[https://www.uniprot.org/uniprot/BIODA_ARATH BIODA_ARATH] Bifunctional enzyme that catalyzes two different reactions involved in the biotin biosynthesis. Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring. Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 21:
==See Also==
==See Also==
-
*[[7%2C8-diaminopelargonic acid synthetase|7%2C8-diaminopelargonic acid synthetase]]
+
*[[7%2C8-diaminopelargonic acid synthase 3D structures|7%2C8-diaminopelargonic acid synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Arath]]
+
[[Category: Arabidopsis thaliana]]
-
[[Category: Alban, C]]
+
[[Category: Large Structures]]
-
[[Category: Cobessi, D]]
+
[[Category: Alban C]]
-
[[Category: Dumas, R]]
+
[[Category: Cobessi D]]
-
[[Category: Ferrer, J L]]
+
[[Category: Dumas R]]
-
[[Category: Meinguet, C]]
+
[[Category: Ferrer JL]]
-
[[Category: Pautre, V]]
+
[[Category: Meinguet C]]
-
[[Category: Bio3-bio1]]
+
[[Category: Pautre V]]
-
[[Category: Biotin synthesis]]
+
-
[[Category: Transferase]]
+

Current revision

Structure of bifunctional DAPA aminotransferase-DTB synthetase from Arabidopsis thaliana in its apo form.

PDB ID 4a0g

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4a0g"
Personal tools