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3b6n

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==Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase PV003920 from Plasmodium vivax==
==Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase PV003920 from Plasmodium vivax==
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<StructureSection load='3b6n' size='340' side='right' caption='[[3b6n]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
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<StructureSection load='3b6n' size='340' side='right'caption='[[3b6n]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3b6n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plavs Plavs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B6N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3B6N FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3b6n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_vivax_Sal-1 Plasmodium vivax Sal-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B6N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B6N FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.26&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PV003920, PVX_003920 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=126793 PLAVS])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_2,4-cyclodiphosphate_synthase 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.12 4.6.1.12] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b6n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b6n OCA], [https://pdbe.org/3b6n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b6n RCSB], [https://www.ebi.ac.uk/pdbsum/3b6n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b6n ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b6n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b6n OCA], [http://pdbe.org/3b6n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3b6n RCSB], [http://www.ebi.ac.uk/pdbsum/3b6n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3b6n ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A5KBP6_PLAVS A5KBP6_PLAVS]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/3b6n_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/3b6n_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase]]
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[[Category: Large Structures]]
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[[Category: Plavs]]
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[[Category: Plasmodium vivax Sal-1]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Artz, J D]]
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[[Category: Artz JD]]
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[[Category: Bochkarev, A]]
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[[Category: Bochkarev A]]
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[[Category: Edwards, A M]]
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[[Category: Edwards AM]]
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[[Category: Hui, R]]
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[[Category: Hui R]]
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[[Category: Khuu, C]]
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[[Category: Khuu C]]
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[[Category: Kozieradzki, I]]
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[[Category: Kozieradzki I]]
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[[Category: Lew, J]]
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[[Category: Lew J]]
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[[Category: Lin, Y H]]
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[[Category: Lin YH]]
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[[Category: Structural genomic]]
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[[Category: Schapira M]]
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[[Category: Schapira, M]]
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[[Category: Sun X]]
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[[Category: Sun, X]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J]]
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[[Category: Wernimont AK]]
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[[Category: Wernimont, A K]]
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[[Category: Xiao T]]
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[[Category: Xiao, T]]
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[[Category: Zhao Y]]
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[[Category: Zhao, Y]]
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[[Category: Isoprene biosynthesis]]
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[[Category: Lyase]]
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[[Category: Malaria isoprenoid biosynthesis and prenylation pathways ispf]]
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[[Category: Sgc]]
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Current revision

Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase PV003920 from Plasmodium vivax

PDB ID 3b6n

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