3wq8

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:22, 8 November 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
==Monomer structure of hyperthermophilic beta-glucosidase mutant forming a dodecameric structure in the crystal form==
==Monomer structure of hyperthermophilic beta-glucosidase mutant forming a dodecameric structure in the crystal form==
-
<StructureSection load='3wq8' size='340' side='right' caption='[[3wq8]], [[Resolution|resolution]] 2.81&Aring;' scene=''>
+
<StructureSection load='3wq8' size='340' side='right'caption='[[3wq8]], [[Resolution|resolution]] 2.81&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3wq8]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WQ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WQ8 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3wq8]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WQ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WQ8 FirstGlance]. <br>
-
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3apg|3apg]], [[3wdp|3wdp]]</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.81&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-glucosidase Beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.21 3.2.1.21] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wq8 OCA], [https://pdbe.org/3wq8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wq8 RCSB], [https://www.ebi.ac.uk/pdbsum/3wq8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wq8 ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wq8 OCA], [http://pdbe.org/3wq8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wq8 RCSB], [http://www.ebi.ac.uk/pdbsum/3wq8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wq8 ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q51723_9EURY Q51723_9EURY]
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
One of the beta-glucosidases from Pyrococcus furiosus (BGLPf) is found to be a hyperthermophilic tetrameric enzyme that can degrade cellooligosaccharides. Recently, the crystal structures of the tetrameric and dimeric forms were solved. Here, a new monomeric form of BGLPf was constructed by removing the C-terminal region of the enzyme and its crystal structure was solved at a resolution of 2.8 A in space group P1. It was discovered that the mutant enzyme forms a unique dodecameric structure consisting of two hexameric rings in the asymmetric unit of the crystal. Under biological conditions, the mutant enzyme forms a monomer. This result helps explain how BGLPf has attained its oligomeric structure and thermostability.
 +
 +
Monomer structure of a hyperthermophilic beta-glucosidase mutant forming a dodecameric structure in the crystal form.,Nakabayashi M, Kataoka M, Watanabe M, Ishikawa K Acta Crystallogr F Struct Biol Commun. 2014 Jul;70(Pt 7):854-9. doi:, 10.1107/S2053230X14010188. Epub 2014 Jun 18. PMID:25005077<ref>PMID:25005077</ref>
 +
 +
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 +
</div>
 +
<div class="pdbe-citations 3wq8" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
-
*[[Beta-glucosidase|Beta-glucosidase]]
+
*[[Beta-glucosidase 3D structures|Beta-glucosidase 3D structures]]
-
*[[Galactosidase|Galactosidase]]
+
*[[Galactosidase 3D structures|Galactosidase 3D structures]]
 +
== References ==
 +
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Beta-glucosidase]]
+
[[Category: Large Structures]]
-
[[Category: Ishikawa, K]]
+
[[Category: Pyrococcus furiosus]]
-
[[Category: Kataoka, M]]
+
[[Category: Ishikawa K]]
-
[[Category: Nakabayashi, M]]
+
[[Category: Kataoka M]]
-
[[Category: Watanabe, M]]
+
[[Category: Nakabayashi M]]
-
[[Category: Hydrolase]]
+
[[Category: Watanabe M]]
-
[[Category: Hydrolysis]]
+
-
[[Category: Sugar binding]]
+
-
[[Category: Tim barrel]]
+

Current revision

Monomer structure of hyperthermophilic beta-glucosidase mutant forming a dodecameric structure in the crystal form

PDB ID 3wq8

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3wq8"
Personal tools