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4cwb

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==Staphylococcus aureus 7,8-Dihydro-6-hydroxymethylpterin- pyrophosphokinase in complex with AMPCPP and an inhibitor==
==Staphylococcus aureus 7,8-Dihydro-6-hydroxymethylpterin- pyrophosphokinase in complex with AMPCPP and an inhibitor==
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<StructureSection load='4cwb' size='340' side='right' caption='[[4cwb]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
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<StructureSection load='4cwb' size='340' side='right'caption='[[4cwb]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4cwb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CWB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CWB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4cwb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CWB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CWB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=APC:DIPHOSPHOMETHYLPHOSPHONIC+ACID+ADENOSYL+ESTER'>APC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=X6L:2-AMINO-8-[2-OXO-2-(4-PHENYLPHENYL)ETHYL]SULFANYL-1,9-DIHYDROPURIN-6-ONE'>X6L</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.56&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-amino-4-hydroxy-6-hydroxymethyldihydropteridine_diphosphokinase 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.6.3 2.7.6.3] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=APC:DIPHOSPHOMETHYLPHOSPHONIC+ACID+ADENOSYL+ESTER'>APC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=X6L:2-AMINO-8-[2-OXO-2-(4-PHENYLPHENYL)ETHYL]SULFANYL-1,9-DIHYDROPURIN-6-ONE'>X6L</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cwb OCA], [http://pdbe.org/4cwb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4cwb RCSB], [http://www.ebi.ac.uk/pdbsum/4cwb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4cwb ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cwb OCA], [https://pdbe.org/4cwb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cwb RCSB], [https://www.ebi.ac.uk/pdbsum/4cwb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cwb ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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</div>
</div>
<div class="pdbe-citations 4cwb" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4cwb" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[HPPK 3D structures|HPPK 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase]]
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[[Category: Large Structures]]
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[[Category: Dennis, M L]]
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[[Category: Staphylococcus aureus]]
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[[Category: Peat, T S]]
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[[Category: Dennis ML]]
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[[Category: Swarbrick, J D]]
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[[Category: Peat TS]]
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[[Category: Folate]]
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[[Category: Swarbrick JD]]
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[[Category: Structure-based drug design]]
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[[Category: Transferase]]
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Current revision

Staphylococcus aureus 7,8-Dihydro-6-hydroxymethylpterin- pyrophosphokinase in complex with AMPCPP and an inhibitor

PDB ID 4cwb

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