3c8g

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==Crystal structure of a possible transciptional regulator YggD from Shigella flexneri 2a str. 2457T==
==Crystal structure of a possible transciptional regulator YggD from Shigella flexneri 2a str. 2457T==
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<StructureSection load='3c8g' size='340' side='right' caption='[[3c8g]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='3c8g' size='340' side='right'caption='[[3c8g]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3c8g]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Shigella_flexneri_2a_str._2457t Shigella flexneri 2a str. 2457t]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2hkt 2hkt]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C8G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3C8G FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3c8g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri_2a_str._2457T Shigella flexneri 2a str. 2457T]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C8G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C8G FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yggD, S3120, SF2919 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=198215 Shigella flexneri 2a str. 2457T])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c8g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c8g OCA], [https://pdbe.org/3c8g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c8g RCSB], [https://www.ebi.ac.uk/pdbsum/3c8g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c8g ProSAT], [https://www.topsan.org/Proteins/MCSG/3c8g TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c8g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c8g OCA], [http://pdbe.org/3c8g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3c8g RCSB], [http://www.ebi.ac.uk/pdbsum/3c8g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3c8g ProSAT], [http://www.topsan.org/Proteins/MCSG/3c8g TOPSAN]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FUME_SHIFL FUME_SHIFL] In vitro catalyzes the addition of water to fumarate, forming malate. Cannot catalyze the reverse reaction. Cannot use the cis-isomer maleate as substrate.[UniProtKB:P11663]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c8/3c8g_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c8/3c8g_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Shigella flexneri 2a str. 2457t]]
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[[Category: Large Structures]]
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[[Category: Borovilos, M]]
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[[Category: Shigella flexneri 2a str. 2457T]]
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[[Category: Clancy, S]]
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[[Category: Borovilos M]]
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[[Category: Joachimiak, A]]
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[[Category: Clancy S]]
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[[Category: Structural genomic]]
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[[Category: Joachimiak A]]
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[[Category: Tan, K]]
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[[Category: Tan K]]
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[[Category: Apc27974]]
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[[Category: Mannitol operon repressor]]
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[[Category: Mcsg]]
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[[Category: Methylation]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Transcription regulator]]
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[[Category: Yggd]]
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Current revision

Crystal structure of a possible transciptional regulator YggD from Shigella flexneri 2a str. 2457T

PDB ID 3c8g

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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