4b5q

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==The lytic polysaccharide monooxygenase GH61D structure from the basidiomycota fungus Phanerochaete chrysosporium==
==The lytic polysaccharide monooxygenase GH61D structure from the basidiomycota fungus Phanerochaete chrysosporium==
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<StructureSection load='4b5q' size='340' side='right' caption='[[4b5q]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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<StructureSection load='4b5q' size='340' side='right'caption='[[4b5q]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4b5q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chrysosporium_pruinosum_(gilman_&_abbott)_carmich. Chrysosporium pruinosum (gilman & abbott) carmich.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B5Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B5Q FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4b5q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Phanerodontia_chrysosporium Phanerodontia chrysosporium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B5Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B5Q FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b5q OCA], [http://pdbe.org/4b5q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4b5q RCSB], [http://www.ebi.ac.uk/pdbsum/4b5q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4b5q ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b5q OCA], [https://pdbe.org/4b5q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b5q RCSB], [https://www.ebi.ac.uk/pdbsum/4b5q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b5q ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LP9D_PHACH LP9D_PHACH] Lytic polysaccharide monooxygenase (LPMO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding only C1 oxidation products (PubMed:22132148, PubMed:30238672). Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate (PubMed:22132148).<ref>PMID:22132148</ref> <ref>PMID:30238672</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beckham, G T]]
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[[Category: Large Structures]]
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[[Category: Crowley, M F]]
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[[Category: Phanerodontia chrysosporium]]
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[[Category: Eijsink, V G.H]]
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[[Category: Beckham GT]]
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[[Category: Horn, S J]]
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[[Category: Crowley MF]]
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[[Category: Ishida, T]]
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[[Category: Eijsink VGH]]
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[[Category: Kim, S]]
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[[Category: Horn SJ]]
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[[Category: Larsson, A M]]
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[[Category: Ishida T]]
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[[Category: Payne, C M]]
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[[Category: Kim S]]
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[[Category: Sandgren, M]]
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[[Category: Larsson AM]]
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[[Category: Stahlberg, J]]
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[[Category: Payne CM]]
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[[Category: Westereng, B]]
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[[Category: Sandgren M]]
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[[Category: Wu, M]]
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[[Category: Stahlberg J]]
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[[Category: Cellulose degradation]]
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[[Category: Westereng B]]
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[[Category: Copper monooxygenase]]
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[[Category: Wu M]]
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[[Category: Hydrolase]]
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[[Category: Metal binding site]]
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Current revision

The lytic polysaccharide monooxygenase GH61D structure from the basidiomycota fungus Phanerochaete chrysosporium

PDB ID 4b5q

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