4b5q
From Proteopedia
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==The lytic polysaccharide monooxygenase GH61D structure from the basidiomycota fungus Phanerochaete chrysosporium== | ==The lytic polysaccharide monooxygenase GH61D structure from the basidiomycota fungus Phanerochaete chrysosporium== | ||
- | <StructureSection load='4b5q' size='340' side='right' caption='[[4b5q]], [[Resolution|resolution]] 1.75Å' scene=''> | + | <StructureSection load='4b5q' size='340' side='right'caption='[[4b5q]], [[Resolution|resolution]] 1.75Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[4b5q]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4b5q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Phanerodontia_chrysosporium Phanerodontia chrysosporium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B5Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B5Q FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b5q OCA], [https://pdbe.org/4b5q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b5q RCSB], [https://www.ebi.ac.uk/pdbsum/4b5q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b5q ProSAT]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/LP9D_PHACH LP9D_PHACH] Lytic polysaccharide monooxygenase (LPMO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding only C1 oxidation products (PubMed:22132148, PubMed:30238672). Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate (PubMed:22132148).<ref>PMID:22132148</ref> <ref>PMID:30238672</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: Beckham | + | [[Category: Large Structures]] |
- | [[Category: Crowley | + | [[Category: Phanerodontia chrysosporium]] |
- | [[Category: Eijsink | + | [[Category: Beckham GT]] |
- | [[Category: Horn | + | [[Category: Crowley MF]] |
- | [[Category: Ishida | + | [[Category: Eijsink VGH]] |
- | [[Category: Kim | + | [[Category: Horn SJ]] |
- | [[Category: Larsson | + | [[Category: Ishida T]] |
- | [[Category: Payne | + | [[Category: Kim S]] |
- | [[Category: Sandgren | + | [[Category: Larsson AM]] |
- | [[Category: Stahlberg | + | [[Category: Payne CM]] |
- | [[Category: Westereng | + | [[Category: Sandgren M]] |
- | [[Category: Wu | + | [[Category: Stahlberg J]] |
- | + | [[Category: Westereng B]] | |
- | + | [[Category: Wu M]] | |
- | + | ||
- | + |
Current revision
The lytic polysaccharide monooxygenase GH61D structure from the basidiomycota fungus Phanerochaete chrysosporium
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Categories: Large Structures | Phanerodontia chrysosporium | Beckham GT | Crowley MF | Eijsink VGH | Horn SJ | Ishida T | Kim S | Larsson AM | Payne CM | Sandgren M | Stahlberg J | Westereng B | Wu M