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4k8l

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==Crystal structure of a putative 4-hydroxyproline epimerase/3-hydroxyproline dehydratse from the soil bacterium ochrobacterium anthropi, target efi-506495, disordered loops==
==Crystal structure of a putative 4-hydroxyproline epimerase/3-hydroxyproline dehydratse from the soil bacterium ochrobacterium anthropi, target efi-506495, disordered loops==
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<StructureSection load='4k8l' size='340' side='right' caption='[[4k8l]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='4k8l' size='340' side='right'caption='[[4k8l]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4k8l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ocha4 Ocha4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K8L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K8L FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4k8l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Brucella_anthropi_ATCC_49188 Brucella anthropi ATCC 49188]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K8L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K8L FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Oant_0439 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=439375 OCHA4])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k8l OCA], [http://pdbe.org/4k8l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4k8l RCSB], [http://www.ebi.ac.uk/pdbsum/4k8l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4k8l ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k8l OCA], [https://pdbe.org/4k8l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k8l RCSB], [https://www.ebi.ac.uk/pdbsum/4k8l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k8l ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/4HPE1_BRUA4 4HPE1_BRUA4] Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp) in vitro, albeit with low efficiency. The physiological substrate may be different. Displays no proline racemase activity.<ref>PMID:24980702</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ocha4]]
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[[Category: Brucella anthropi ATCC 49188]]
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[[Category: Almo, S C]]
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[[Category: Large Structures]]
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[[Category: Bhosle, R]]
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[[Category: Al Obaidi NF]]
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[[Category: Chowdhury, S]]
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[[Category: Almo SC]]
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[[Category: EFI, Enzyme Function Initiative]]
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[[Category: Bhosle R]]
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[[Category: Evens, B]]
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[[Category: Chowdhury S]]
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[[Category: Gerlt, J A]]
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[[Category: Evens B]]
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[[Category: Glen, A Scott]]
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[[Category: Gerlt JA]]
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[[Category: Hammonds, J]]
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[[Category: Hammonds J]]
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[[Category: Hillerich, B]]
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[[Category: Hillerich B]]
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[[Category: Imker, H J]]
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[[Category: Imker HJ]]
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[[Category: Love, J]]
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[[Category: Love J]]
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[[Category: Morisco, L L]]
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[[Category: Morisco LL]]
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[[Category: Obaidi, N F.Al]]
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[[Category: Scott Glen A]]
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[[Category: Seidel, R D]]
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[[Category: Seidel RD]]
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[[Category: Sojitra, S]]
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[[Category: Sojitra S]]
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[[Category: Stead, M]]
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[[Category: Stead M]]
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[[Category: Toro, R]]
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[[Category: Toro R]]
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[[Category: Vetting, M W]]
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[[Category: Vetting MW]]
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[[Category: Washington, E]]
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[[Category: Washington E]]
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[[Category: Wasserman, S R]]
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[[Category: Wasserman SR]]
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[[Category: Efi]]
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[[Category: Enzyme function initiative]]
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[[Category: Enzyme function intiative]]
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[[Category: Isomerase]]
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[[Category: Proline racemase]]
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[[Category: Proposed 3-oh proline dehydratase]]
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[[Category: Structural genomic]]
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Current revision

Crystal structure of a putative 4-hydroxyproline epimerase/3-hydroxyproline dehydratse from the soil bacterium ochrobacterium anthropi, target efi-506495, disordered loops

PDB ID 4k8l

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