4q3g

From Proteopedia

(Difference between revisions)

Current revision

Structure of the OsSERK2 leucine rich repeat extracellular domain

Structural highlights

4q3g is a 2 chain structure with sequence from Oryza sativa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.787Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q01JP8_ORYSA

Publication Abstract from PubMed

Somatic embryogenesis receptor kinases (SERKs) are leucine-rich repeat (LRR)-containing integral membrane receptors that are involved in the regulation of development and immune responses in plants. It has recently been shown that rice SERK2 (OsSERK2) is essential for XA21-mediated resistance to the pathogen Xanthomonas oryzae pv. oryzae. OsSERK2 is also required for the BRI1-mediated, FLS2-mediated and EFR-mediated responses to brassinosteroids, flagellin and elongation factor Tu (EF-Tu), respectively. Here, crystal structures of the LRR domains of OsSERK2 and a D128N OsSERK2 mutant, expressed as hagfish variable lymphocyte receptor (VLR) fusions, are reported. These structures suggest that the aspartate mutation does not generate any significant conformational change in the protein, but instead leads to an altered interaction with partner receptors.

Structure of the OsSERK2 leucine-rich repeat extracellular domain.,McAndrew R, Pruitt RN, Kamita SG, Pereira JH, Majumdar D, Hammock BD, Adams PD, Ronald PC Acta Crystallogr D Biol Crystallogr. 2014 Nov;70(Pt 11):3080-6. doi:, 10.1107/S1399004714021178. Epub 2014 Oct 29. PMID:25372696^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ McAndrew R, Pruitt RN, Kamita SG, Pereira JH, Majumdar D, Hammock BD, Adams PD, Ronald PC. Structure of the OsSERK2 leucine-rich repeat extracellular domain. Acta Crystallogr D Biol Crystallogr. 2014 Nov;70(Pt 11):3080-6. doi:, 10.1107/S1399004714021178. Epub 2014 Oct 29. PMID:25372696 doi:http://dx.doi.org/10.1107/S1399004714021178

1 Structural highlights
2 Function
3 Publication Abstract from PubMed
4 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4q3g"

@@ Line 1: / Line 1: @@
 ==Structure of the OsSERK2 leucine rich repeat extracellular domain==
-<StructureSection load='4q3g' size='340' side='right' caption='[[4q3g]], [[Resolution|resolution]] 2.79&Aring;' scene=''>
+<StructureSection load='4q3g' size='340' side='right'caption='[[4q3g]], [[Resolution|resolution]] 2.79&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4q3g]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q3G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q3G FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4q3g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa Oryza sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q3G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q3G FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.787&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4q3i|4q3i]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q3g OCA], [http://pdbe.org/4q3g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q3g RCSB], [http://www.ebi.ac.uk/pdbsum/4q3g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q3g ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q3g OCA], [https://pdbe.org/4q3g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q3g RCSB], [https://www.ebi.ac.uk/pdbsum/4q3g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q3g ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q01JP8_ORYSA Q01JP8_ORYSA]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 21: / Line 23: @@
 __TOC__
 </StructureSection>
-[[Category: Adams, P D]]
+[[Category: Large Structures]]
-[[Category: Hammock, B D]]
+[[Category: Oryza sativa]]
-[[Category: Kamita, S G]]
+[[Category: Adams PD]]
-[[Category: Majumder, D]]
+[[Category: Hammock BD]]
-[[Category: McAndrew, R P]]
+[[Category: Kamita SG]]
-[[Category: Pereira, J H]]
+[[Category: Majumder D]]
-[[Category: Pruitt, R N]]
+[[Category: McAndrew RP]]
-[[Category: Ronald, P C]]
+[[Category: Pereira JH]]
-[[Category: Brassinosteroid]]
+[[Category: Pruitt RN]]
-[[Category: Leucine rich repeat]]
+[[Category: Ronald PC]]
-[[Category: Toll-like receptor]]
-[[Category: Transferase]]

4q3g

From Proteopedia

Current revision

Structure of the OsSERK2 leucine rich repeat extracellular domain

Structural highlights

Function

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

Personal tools

Navigation

Search

Toolbox