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Superoxide Reductase

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Current revision (10:44, 10 December 2023) (edit) (undo)
 
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<StructureSection load='2ji3' size='450' side='right' caption='Superoxide Reductase with Fe+3 ion (orange) complex with peroxide (red), Ca+2 ion (green) and nitrate (PDB entry [[2ji3]])' scene='41/417537/Cv/3'>
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<StructureSection load='' size='350' side='right' caption='Superoxide Reductase with Fe+3 ion (orange) complex with peroxide (red), Ca+2 ion (green) and nitrate (PDB entry [[2ji3]])' scene='41/417537/Cv/3'>
== Function ==
== Function ==
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== Structural highlights ==
== Structural highlights ==
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The <scene name='41/417537/Cv/5'>active site of SOR contains Fe+3 ion and peroxide</scene><ref>PMID:17446401</ref>. Water molecules shown as red spheres.
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The <scene name='41/417537/Cv/6'>active site of SOR contains Fe+3 ion and peroxide</scene><ref>PMID:17446401</ref>. Water molecules are shown as red spheres.
</StructureSection>
</StructureSection>
== 3D Structures of Superoxide Reductase ==
== 3D Structures of Superoxide Reductase ==
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[[2ji3]] - DbSOR (mutant)+Fe(III)+peroxide<br />
[[2ji3]] - DbSOR (mutant)+Fe(III)+peroxide<br />
[[1vzg]], [[1vzh]], [[1vzi]] - DbSOR (mutant)+Fe(III)+Fe2(CN)6<br />
[[1vzg]], [[1vzh]], [[1vzi]] - DbSOR (mutant)+Fe(III)+Fe2(CN)6<br />
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[[1y07]] – SOR+Fe(III) – ''Treponema pallidum''<br />
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[[1y07]] – SOR + Fe(III) – ''Treponema pallidum''<br />
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[[1dqi]], [[1dqk]], [[1do6]] – SOR+Fe(III) – ''Pyrococcus furiosus''<br />
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[[1dqi]], [[1dqk]], [[1do6]] – SOR + Fe(III) – ''Pyrococcus furiosus''<br />
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[[4d7p]] – SOR + Fe(III) – ''Giardia intestinalis''<br />
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[[6gq8]] – SOR + Fe(III) – ''Nanoarchaeum equitans''<br />
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[[4brv]] – IhSOR + Fe (II) – ''Ignicoccus hospitalis''<br />
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[[4brj]], [[4brv]] – IhSOR (mutant) + Fe (II) <br />
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== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Superoxide Reductase with Fe+3 ion (orange) complex with peroxide (red), Ca+2 ion (green) and nitrate (PDB entry 2ji3)

Drag the structure with the mouse to rotate

3D Structures of Superoxide Reductase

Updated on 10-December-2023

2ji1 – DbSOR+Fe(II)+Fe(III) – Desulfovibrio baarsii
2ji2 – DbSOR (mutant)+Fe(II)+Fe(III)
4bff – AfSOR + Fe (II) – Archaeoglobus fulgidus
4c4b, 4c4u – AfSOR (mutant) + Fe (II)
4bgl – AfSOR + Fe (III)
4bfj, 4bfk - AfSOR (mutant)+Fe(III)
2ji3 - DbSOR (mutant)+Fe(III)+peroxide
1vzg, 1vzh, 1vzi - DbSOR (mutant)+Fe(III)+Fe2(CN)6
1y07 – SOR + Fe(III) – Treponema pallidum
1dqi, 1dqk, 1do6 – SOR + Fe(III) – Pyrococcus furiosus
4d7p – SOR + Fe(III) – Giardia intestinalis
6gq8 – SOR + Fe(III) – Nanoarchaeum equitans
4brv – IhSOR + Fe (II) – Ignicoccus hospitalis
4brj, 4brv – IhSOR (mutant) + Fe (II)

References

  1. Imlay JA. What biological purpose is served by superoxide reductase? J Biol Inorg Chem. 2002 Jun;7(6):659-63. Epub 2002 Apr 11. PMID:12072974 doi:http://dx.doi.org/10.1007/s00775-002-0361-3
  2. Katona G, Carpentier P, Niviere V, Amara P, Adam V, Ohana J, Tsanov N, Bourgeois D. Raman-assisted crystallography reveals end-on peroxide intermediates in a nonheme iron enzyme. Science. 2007 Apr 20;316(5823):449-53. PMID:17446401 doi:316/5823/449

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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