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2n0c
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==NMR structure of Neuromedin C in 10% TFE== | ==NMR structure of Neuromedin C in 10% TFE== | ||
| - | <StructureSection load='2n0c' size='340' side='right' caption='[[2n0c | + | <StructureSection load='2n0c' size='340' side='right'caption='[[2n0c]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2n0c]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N0C OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[2n0c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N0C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N0C FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n0c OCA], [https://pdbe.org/2n0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n0c RCSB], [https://www.ebi.ac.uk/pdbsum/2n0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n0c ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/GRP_HUMAN GRP_HUMAN] GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression, long-term potentiation, and amygdala-dependent memory for fear (By similarity). |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Adrover M]] |
| - | [[Category: | + | [[Category: Martorell G]] |
| - | [[Category: | + | [[Category: Pauwels K]] |
| - | [[Category: | + | [[Category: Perez J]] |
| - | [[Category: | + | [[Category: Sanchis P]] |
| - | [[Category: | + | [[Category: Vilanova B]] |
| - | + | ||
Current revision
NMR structure of Neuromedin C in 10% TFE
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