5l2r

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==Crystal structure of fumarate hydratase from Leishmania major==
==Crystal structure of fumarate hydratase from Leishmania major==
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<StructureSection load='5l2r' size='340' side='right' caption='[[5l2r]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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<StructureSection load='5l2r' size='340' side='right'caption='[[5l2r]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5l2r]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L2R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L2R FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5l2r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L2R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5L2R FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LMR:(2S)-2-HYDROXYBUTANEDIOIC+ACID'>LMR</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.054&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fumarate_hydratase Fumarate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.2 4.2.1.2] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LMR:(2S)-2-HYDROXYBUTANEDIOIC+ACID'>LMR</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l2r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l2r OCA], [http://pdbe.org/5l2r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l2r RCSB], [http://www.ebi.ac.uk/pdbsum/5l2r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l2r ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5l2r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l2r OCA], [https://pdbe.org/5l2r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5l2r RCSB], [https://www.ebi.ac.uk/pdbsum/5l2r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5l2r ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FUM2_LEIMA FUM2_LEIMA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Fumarate hydratase]]
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[[Category: Large Structures]]
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[[Category: Drennan, C L]]
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[[Category: Leishmania major]]
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[[Category: Feliciano, P R]]
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[[Category: Drennan CL]]
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[[Category: Nonato, M C]]
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[[Category: Feliciano PR]]
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[[Category: Fumarate hydratase fe-s cluster]]
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[[Category: Nonato MC]]
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[[Category: Lyase]]
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Crystal structure of fumarate hydratase from Leishmania major

PDB ID 5l2r

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