5hyw

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==The crystal structure of the D3-ASK1 complex==
==The crystal structure of the D3-ASK1 complex==
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<StructureSection load='5hyw' size='340' side='right' caption='[[5hyw]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
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<StructureSection load='5hyw' size='340' side='right'caption='[[5hyw]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5hyw]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HYW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HYW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5hyw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] and [https://en.wikipedia.org/wiki/Oryza_sativa_Japonica_Group Oryza sativa Japonica Group]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HYW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HYW FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5hzg|5hzg]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.01&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hyw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hyw OCA], [http://pdbe.org/5hyw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hyw RCSB], [http://www.ebi.ac.uk/pdbsum/5hyw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hyw ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hyw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hyw OCA], [https://pdbe.org/5hyw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hyw RCSB], [https://www.ebi.ac.uk/pdbsum/5hyw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hyw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MAX2_ORYSJ MAX2_ORYSJ]] Controls tillering by suppressing axillary bud activity. Tiller is a specialized grain-bearing branch that is formed on the unelongated basal internode and grows independently of the mother stem (culm) by means of its own adventitious roots. Is necessary for responses to strigolactones and the establishment of arbuscular mycorrhiza symbiosis in rice. May be involved in the ubiquitin-mediated degradation of specific proteins that activate axillary growth. D3 is crucial for establishing arbuscular mycorrhiza (AM) symbiosis in rice, whereas D14 and D14-LIKE are not. Our results suggest distinct roles for these SL-related components in AM symbiosis. [[http://www.uniprot.org/uniprot/SKP1A_ARATH SKP1A_ARATH]] Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends of the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1. SCF(UFO) is required for vegetative and floral organ development as well as for male gametogenesis. SCF(TIR1) is involved in auxin signaling pathway. SCF(COI1) regulates responses to jasmonates. SCF(EID1) and SCF(AFR) are implicated in phytochrome A light signaling. SCF(ADO1), SCF(ADO2), SCF(ADO3) are related to the circadian clock. SCF(ORE9) seems to be involved in senescence. SCF(EBF1/EBF2) may regulate ethylene signaling. Plays a role during embryogenesis and early postembryonic development, especially during cell elongation and division. Contributes to the correct chromosome segregation during tetrad formation.<ref>PMID:10528262</ref> <ref>PMID:10398681</ref> <ref>PMID:10500191</ref> <ref>PMID:11526079</ref> <ref>PMID:12970487</ref> <ref>PMID:14688296</ref>
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[https://www.uniprot.org/uniprot/MAX2_ORYSJ MAX2_ORYSJ] Controls tillering by suppressing axillary bud activity. Tiller is a specialized grain-bearing branch that is formed on the unelongated basal internode and grows independently of the mother stem (culm) by means of its own adventitious roots. Is necessary for responses to strigolactones and the establishment of arbuscular mycorrhiza symbiosis in rice. May be involved in the ubiquitin-mediated degradation of specific proteins that activate axillary growth. D3 is crucial for establishing arbuscular mycorrhiza (AM) symbiosis in rice, whereas D14 and D14-LIKE are not. Our results suggest distinct roles for these SL-related components in AM symbiosis.
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lou, Z Y]]
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[[Category: Arabidopsis thaliana]]
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[[Category: Ming, Z H]]
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[[Category: Large Structures]]
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[[Category: Rao, Z H]]
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[[Category: Oryza sativa Japonica Group]]
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[[Category: Xie, D X]]
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[[Category: Lou ZY]]
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[[Category: Yan, L M]]
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[[Category: Ming ZH]]
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[[Category: Yao, R F]]
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[[Category: Rao ZH]]
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[[Category: F-box protein]]
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[[Category: Xie DX]]
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[[Category: Signaling protein-protein binding complex]]
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[[Category: Yan LM]]
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[[Category: Yao RF]]

Current revision

The crystal structure of the D3-ASK1 complex

PDB ID 5hyw

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