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5ihe

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==D-family DNA polymerase - DP1 subunit (3'-5' proof-reading exonuclease)==
==D-family DNA polymerase - DP1 subunit (3'-5' proof-reading exonuclease)==
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<StructureSection load='5ihe' size='340' side='right' caption='[[5ihe]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='5ihe' size='340' side='right'caption='[[5ihe]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ihe]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IHE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IHE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ihe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_abyssi_GE5 Pyrococcus abyssi GE5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IHE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IHE FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=D5M:2-DEOXYADENOSINE-5-MONOPHOSPHATE'>D5M</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=D5M:2-DEOXYADENOSINE-5-MONOPHOSPHATE'>D5M</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ihe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ihe OCA], [http://pdbe.org/5ihe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ihe RCSB], [http://www.ebi.ac.uk/pdbsum/5ihe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ihe ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ihe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ihe OCA], [https://pdbe.org/5ihe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ihe RCSB], [https://www.ebi.ac.uk/pdbsum/5ihe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ihe ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DP2S_PYRAB DP2S_PYRAB]] Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
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[https://www.uniprot.org/uniprot/DP2S_PYRAB DP2S_PYRAB] Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5ihe" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5ihe" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: DNA-directed DNA polymerase]]
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[[Category: Large Structures]]
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[[Category: Larue, M De]]
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[[Category: Pyrococcus abyssi GE5]]
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[[Category: Raia, P]]
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[[Category: De Larue M]]
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[[Category: Sauguet, L]]
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[[Category: Raia P]]
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[[Category: Dna polymerase d-family exonuclease]]
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[[Category: Sauguet L]]
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[[Category: Transferase]]
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Current revision

D-family DNA polymerase - DP1 subunit (3'-5' proof-reading exonuclease)

PDB ID 5ihe

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