1oj1

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[[Image:1oj1.jpg|left|200px]]
 
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{{Structure
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==Nonproductive and Novel Binding Modes in Cytotoxic Ribonucleases from Rana catesbeiana of Two Crystal Structures Complexed with (2,5 CpG) and d(ApCpGpA)==
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|PDB= 1oj1 |SIZE=350|CAPTION= <scene name='initialview01'>1oj1</scene>, resolution 2.1&Aring;
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<StructureSection load='1oj1' size='340' side='right'caption='[[1oj1]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Chain+A'>AC1</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=CG2:CYTIDYL-2&#39;-5&#39;-PHOSPHO-GUANOSINE'>CG2</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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<table><tr><td colspan='2'>[[1oj1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lithobates_catesbeianus Lithobates catesbeianus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OJ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OJ1 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CG2:CYTIDYL-2-5-PHOSPHO-GUANOSINE'>CG2</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oj1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oj1 OCA], [https://pdbe.org/1oj1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oj1 RCSB], [https://www.ebi.ac.uk/pdbsum/1oj1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oj1 ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1oj1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oj1 OCA], [http://www.ebi.ac.uk/pdbsum/1oj1 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1oj1 RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/Q9DFY5_LITCT Q9DFY5_LITCT]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oj/1oj1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1oj1 ConSurf].
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<div style="clear:both"></div>
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'''NONPRODUCTIVE AND NOVEL BINDING MODES IN CYTOTOXIC RIBONUCLEASES FROM RANA CATESBEIANA OF TWO CRYSTAL STRUCTURES COMPLEXED WITH (2,5 CPG) AND D(APCPGPA)'''
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==See Also==
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1OJ1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rana_catesbeiana Rana catesbeiana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OJ1 OCA].
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[[Category: Large Structures]]
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[[Category: Rana catesbeiana]]
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[[Category: Lithobates catesbeianus]]
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[[Category: Single protein]]
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[[Category: Chen L-y]]
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[[Category: Chen, L Y.]]
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[[Category: Cheng P-T]]
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[[Category: Cheng, P T.]]
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[[Category: Liao Y-D]]
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[[Category: Liao, Y D.]]
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[[Category: Liu J-H]]
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[[Category: Liu, J H.]]
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[[Category: Sun Y-J]]
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[[Category: Sun, Y J.]]
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[[Category: Tsai C-J]]
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[[Category: Tsai, C J.]]
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[[Category: anti-tumor activity]]
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[[Category: cytotoxic ribonuclease]]
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[[Category: hydrolase]]
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[[Category: sialic binding and nucleotide binding]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:46:02 2008''
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Current revision

Nonproductive and Novel Binding Modes in Cytotoxic Ribonucleases from Rana catesbeiana of Two Crystal Structures Complexed with (2,5 CpG) and d(ApCpGpA)

PDB ID 1oj1

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