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5sye
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5sye is ON HOLD Authors: Kellogg, E.H., Nogales, E. Description: Near-atomic resolution cryo-EM reconstruction of doubly bound Taxol-and peloruside...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Near-atomic resolution cryo-EM reconstruction of doubly bound Taxol- and peloruside-stabilized microtubule== | |
| + | <SX load='5sye' size='340' side='right' viewer='molstar' caption='[[5sye]], [[Resolution|resolution]] 3.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5sye]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SYE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SYE FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POU:PELORUSIDE+A'>POU</scene>, <scene name='pdbligand=TA1:TAXOL'>TA1</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5sye FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5sye OCA], [https://pdbe.org/5sye PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5sye RCSB], [https://www.ebi.ac.uk/pdbsum/5sye PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5sye ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TBA1B_PIG TBA1B_PIG] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | ||
| - | + | ==See Also== | |
| - | + | *[[Tubulin 3D Structures|Tubulin 3D Structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </SX> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Kellogg | + | [[Category: Sus scrofa]] |
| + | [[Category: Kellogg EH]] | ||
| + | [[Category: Nogales E]] | ||
Current revision
Near-atomic resolution cryo-EM reconstruction of doubly bound Taxol- and peloruside-stabilized microtubule
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