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5syg
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5syg is ON HOLD Authors: Kellogg, E.H., Hejab, N.M.A., Nogales, E. Description: Cryo-EM reconstruction of zampanolide-bound microtubule [[Category:...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM reconstruction of zampanolide-bound microtubule== | |
| + | <SX load='5syg' size='340' side='right' viewer='molstar' caption='[[5syg]], [[Resolution|resolution]] 3.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5syg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SYG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SYG FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZPN:(2Z,4E)-N-[(S)-[(1S,2E,5S,8E,10Z,17S)-3,11-DIMETHYL-19-METHYLIDENE-7,13-DIOXO-6,21-DIOXABICYCLO[15.3.1]HENICOSA-2,8,10-TRIEN-5-YL](HYDROXY)METHYL]HEXA-2,4-DIENAMIDE'>ZPN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5syg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5syg OCA], [https://pdbe.org/5syg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5syg RCSB], [https://www.ebi.ac.uk/pdbsum/5syg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5syg ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TBA1B_PIG TBA1B_PIG] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | ||
| - | + | ==See Also== | |
| - | + | *[[Tubulin 3D Structures|Tubulin 3D Structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </SX> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Kellogg | + | [[Category: Sus scrofa]] |
| - | [[Category: | + | [[Category: Hejab NMA]] |
| + | [[Category: Kellogg EH]] | ||
| + | [[Category: Nogales E]] | ||
Current revision
Cryo-EM reconstruction of zampanolide-bound microtubule
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