5t37
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5t37 is ON HOLD Authors: Luz, J.G., Antonysamy, S., Partridge, K., Fisher, M. Description: crystal structure of mPGES-1 bound to inhibitor [[Catego...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==crystal structure of mPGES-1 bound to inhibitor== | |
| + | <StructureSection load='5t37' size='340' side='right'caption='[[5t37]], [[Resolution|resolution]] 1.76Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5t37]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T37 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5T37 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.761Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=758:2-CHLORO-5-{[(2,2-DIMETHYLPROPANOYL)AMINO]METHYL}-N-(1H-IMIDAZOL-2-YL)BENZAMIDE'>758</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5t37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t37 OCA], [https://pdbe.org/5t37 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5t37 RCSB], [https://www.ebi.ac.uk/pdbsum/5t37 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5t37 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PTGES_HUMAN PTGES_HUMAN] Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).<ref>PMID:18682561</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Prostaglandin E synthase|Prostaglandin E synthase]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| + | [[Category: Antonysamy S]] | ||
| + | [[Category: Fisher M]] | ||
| + | [[Category: Luz JG]] | ||
| + | [[Category: Partridge K]] | ||
Current revision
crystal structure of mPGES-1 bound to inhibitor
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