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5ixb

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==Structure of human Melanoma Inhibitory Activity (MIA) Protein in complex with Pyrimidin-2-amine==
==Structure of human Melanoma Inhibitory Activity (MIA) Protein in complex with Pyrimidin-2-amine==
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<StructureSection load='5ixb' size='340' side='right' caption='[[5ixb]], [[Resolution|resolution]] 1.39&Aring;' scene=''>
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<StructureSection load='5ixb' size='340' side='right'caption='[[5ixb]], [[Resolution|resolution]] 1.39&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ixb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IXB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IXB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ixb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IXB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IXB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=LGA:PYRIMIDIN-2-AMINE'>LGA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.39&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ixb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ixb OCA], [http://pdbe.org/5ixb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ixb RCSB], [http://www.ebi.ac.uk/pdbsum/5ixb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ixb ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=LGA:PYRIMIDIN-2-AMINE'>LGA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ixb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ixb OCA], [https://pdbe.org/5ixb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ixb RCSB], [https://www.ebi.ac.uk/pdbsum/5ixb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ixb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MIA_HUMAN MIA_HUMAN]] Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.
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[https://www.uniprot.org/uniprot/MIA_HUMAN MIA_HUMAN] Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Autzen, J]]
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[[Category: Homo sapiens]]
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[[Category: Gasper, R]]
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[[Category: Large Structures]]
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[[Category: Hofmann, E]]
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[[Category: Autzen J]]
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[[Category: Puetz, S]]
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[[Category: Gasper R]]
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[[Category: Scherkenbeck, J]]
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[[Category: Hofmann E]]
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[[Category: Seibel, N]]
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[[Category: Puetz S]]
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[[Category: Stoll, R]]
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[[Category: Scherkenbeck J]]
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[[Category: Yip, K T]]
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[[Category: Seibel N]]
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[[Category: Zhong, X Y]]
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[[Category: Stoll R]]
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[[Category: All beta]]
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[[Category: Yip KT]]
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[[Category: Cell adhesion]]
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[[Category: Zhong XY]]
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[[Category: Extracellular]]
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[[Category: Sh3 domain-like fold]]
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Current revision

Structure of human Melanoma Inhibitory Activity (MIA) Protein in complex with Pyrimidin-2-amine

PDB ID 5ixb

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