5syb
From Proteopedia
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==Crystal structure of human PHF5A== | ==Crystal structure of human PHF5A== | ||
| - | <StructureSection load='5syb' size='340' side='right' caption='[[5syb]], [[Resolution|resolution]] 1.82Å' scene=''> | + | <StructureSection load='5syb' size='340' side='right'caption='[[5syb]], [[Resolution|resolution]] 1.82Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5syb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SYB OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5syb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SYB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SYB FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5syb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5syb OCA], [https://pdbe.org/5syb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5syb RCSB], [https://www.ebi.ac.uk/pdbsum/5syb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5syb ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PHF5A_HUMAN PHF5A_HUMAN] Acts as a transcriptional regulator by binding to the GJA1/Cx43 promoter and enhancing its up-regulation by ESR1/ER-alpha. Also involved in pre-mRNA splicing.<ref>PMID:12234937</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Fekkes P]] |
| - | + | [[Category: Larsen NA]] | |
| - | + | [[Category: Teng T]] | |
| - | [[Category: | + | [[Category: Tsai JHC]] |
| - | [[Category: | + | [[Category: Zhu P]] |
| - | [[Category: | + | |
| - | [[Category: | + | |
Current revision
Crystal structure of human PHF5A
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Categories: Homo sapiens | Large Structures | Fekkes P | Larsen NA | Teng T | Tsai JHC | Zhu P
