5ltg
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Citrate-bound Pichia angusta Atg18== | |
| - | + | <StructureSection load='5ltg' size='340' side='right'caption='[[5ltg]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ltg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ogataea_angusta Ogataea angusta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LTG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LTG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ltg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ltg OCA], [https://pdbe.org/5ltg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ltg RCSB], [https://www.ebi.ac.uk/pdbsum/5ltg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ltg ProSAT]</span></td></tr> |
| - | [[Category: Kuhnel | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ATG18_PICAN ATG18_PICAN] The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct ATG9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ogataea angusta]] | ||
| + | [[Category: Kuhnel K]] | ||
| + | [[Category: Scacioc A]] | ||
Current revision
Citrate-bound Pichia angusta Atg18
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