This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5lug
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5lug is ON HOLD Authors: Srikannathasan, V., Gileadi, C., Talon, R., Shrestha, L, Kopec, J, Szykowska, A., Burgess-Brown, N., Arrowsmith, C.H., Edwa...) |
|||
| (4 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human Spindlin-2B protein in complex with ART(M3L)QTA(2MR)KS peptide== | |
| + | <StructureSection load='5lug' size='340' side='right'caption='[[5lug]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5lug]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LUG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LUG FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lug OCA], [https://pdbe.org/5lug PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lug RCSB], [https://www.ebi.ac.uk/pdbsum/5lug PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lug ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SPI2B_HUMAN SPI2B_HUMAN] Involved in the regulation of cell cycle progression, this activity is related to the inhibition of apoptosis following the removal of essential growth factors (PubMed:12145692). Exhibits H3K4me3-binding activity (PubMed:29061846).<ref>PMID:12145692</ref> <ref>PMID:29061846</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Spindlin|Spindlin]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: Burgess-Brown | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Huber | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| - | [[Category: | + | [[Category: Bountra C]] |
| - | [[Category: | + | [[Category: Burgess-Brown N]] |
| - | [[Category: | + | [[Category: Edwards AM]] |
| - | [[Category: | + | [[Category: Gileadi C]] |
| - | [[Category: Talon | + | [[Category: Huber K]] |
| - | [[Category: | + | [[Category: Kopec J]] |
| + | [[Category: Oppermann U]] | ||
| + | [[Category: Shrestha L]] | ||
| + | [[Category: Srikannathasan V]] | ||
| + | [[Category: Szykowska A]] | ||
| + | [[Category: Talon R]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
Crystal structure of human Spindlin-2B protein in complex with ART(M3L)QTA(2MR)KS peptide
| |||||||||||
Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Burgess-Brown N | Edwards AM | Gileadi C | Huber K | Kopec J | Oppermann U | Shrestha L | Srikannathasan V | Szykowska A | Talon R | Von Delft F
