5eqj
From Proteopedia
(Difference between revisions)
(2 intermediate revisions not shown.) | |||
Line 1: | Line 1: | ||
==Crystal structure of the two-subunit tRNA m1A58 methyltransferase from Saccharomyces cerevisiae== | ==Crystal structure of the two-subunit tRNA m1A58 methyltransferase from Saccharomyces cerevisiae== | ||
- | <StructureSection load='5eqj' size='340' side='right' caption='[[5eqj]], [[Resolution|resolution]] 2.20Å' scene=''> | + | <StructureSection load='5eqj' size='340' side='right'caption='[[5eqj]], [[Resolution|resolution]] 2.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[5eqj]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EQJ OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5eqj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EQJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EQJ FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5eqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eqj OCA], [https://pdbe.org/5eqj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5eqj RCSB], [https://www.ebi.ac.uk/pdbsum/5eqj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5eqj ProSAT]</span></td></tr> | |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/TRM6_YEAST TRM6_YEAST] Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Binds RNA. Also required for repression of GCN4 mRNA translation by the upstream open reading frames (uORFs) under conditions of amino acid sufficiency.<ref>PMID:10779558</ref> <ref>PMID:7542616</ref> <ref>PMID:9851972</ref> |
- | + | ||
- | + | ||
- | + | ||
- | + | ==See Also== | |
- | + | *[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]] | |
- | + | ||
- | + | ||
- | + | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Saccharomyces cerevisiae S288C]] |
- | [[Category: | + | [[Category: Fan X]] |
- | [[Category: | + | [[Category: Jiang X]] |
- | [[Category: | + | [[Category: Li X]] |
- | [[Category: | + | [[Category: Teng M]] |
- | [[Category: | + | [[Category: Wang C]] |
- | [[Category: | + | [[Category: Wang M]] |
- | [[Category: | + | [[Category: Zhu Y]] |
- | + | ||
- | + |
Current revision
Crystal structure of the two-subunit tRNA m1A58 methyltransferase from Saccharomyces cerevisiae
|
Categories: Large Structures | Saccharomyces cerevisiae S288C | Fan X | Jiang X | Li X | Teng M | Wang C | Wang M | Zhu Y