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1ows

From Proteopedia

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[[Image:1ows.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of a C49 Phospholipase A2 from Indian cobra reveals carbohydrate binding in the hydrophobic channel==
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|PDB= 1ows |SIZE=350|CAPTION= <scene name='initialview01'>1ows</scene>, resolution 2.30&Aring;
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<StructureSection load='1ows' size='340' side='right'caption='[[1ows]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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<table><tr><td colspan='2'>[[1ows]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Naja_naja Naja naja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OWS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OWS FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ows FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ows OCA], [https://pdbe.org/1ows PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ows RCSB], [https://www.ebi.ac.uk/pdbsum/1ows PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ows ProSAT]</span></td></tr>
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|RELATEDENTRY=[[1lfj|1LFJ]], [[1lff|1LFF]], [[1ln8|1LN8]], [[1mh2|1MH2]], [[1mh7|1MH7]], [[1mh8|1MH8]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ows FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ows OCA], [http://www.ebi.ac.uk/pdbsum/1ows PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ows RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/PA2A2_NAJNA PA2A2_NAJNA] PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ow/1ows_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ows ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of a C49 Phospholipase A2 from Indian cobra reveals carbohydrate binding in the hydrophobic channel'''
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==See Also==
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*[[Phospholipase A2 3D structures|Phospholipase A2 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1OWS is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Naja_naja Naja naja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OWS OCA].
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[[Category: Large Structures]]
[[Category: Naja naja]]
[[Category: Naja naja]]
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[[Category: Phospholipase A(2)]]
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[[Category: Jabeen T]]
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[[Category: Protein complex]]
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[[Category: Jasti J]]
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[[Category: Jabeen, T.]]
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[[Category: Kaur P]]
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[[Category: Jasti, J.]]
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[[Category: Sharma S]]
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[[Category: Kaur, P.]]
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[[Category: Singh N]]
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[[Category: Sharma, S.]]
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[[Category: Singh RK]]
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[[Category: Singh, N.]]
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[[Category: Singh TP]]
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[[Category: Singh, R K.]]
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[[Category: Singh, T P.]]
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[[Category: enzyme]]
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[[Category: phospholipase]]
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[[Category: phospholipid]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:51:32 2008''
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Current revision

Crystal structure of a C49 Phospholipase A2 from Indian cobra reveals carbohydrate binding in the hydrophobic channel

PDB ID 1ows

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