5iwz

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'''Unreleased structure'''
 
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The entry 5iwz is ON HOLD until Paper Publication
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==Synaptonemal complex protein==
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<StructureSection load='5iwz' size='340' side='right'caption='[[5iwz]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5iwz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IWZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IWZ FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.098&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5iwz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iwz OCA], [https://pdbe.org/5iwz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5iwz RCSB], [https://www.ebi.ac.uk/pdbsum/5iwz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5iwz ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SYCP2_MOUSE SYCP2_MOUSE] Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. Plays a role in the assembly of synaptonemal complexes (PubMed:16717126). Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility (PubMed:16717126). Required for insertion of SYCP3 into synaptonemal complexes (PubMed:16717126). May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements.<ref>PMID:11463847</ref> <ref>PMID:16717126</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Cao X]]
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[[Category: Feng J]]
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[[Category: Fu S]]
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[[Category: Liu L]]
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[[Category: Lu J]]
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[[Category: Shen Y]]
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[[Category: Wu H]]
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[[Category: Yang X]]
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[[Category: Zeng M]]

Current revision

Synaptonemal complex protein

PDB ID 5iwz

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