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5jr0
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Domain 4 Segment 6 of voltage-gated sodium channel Nav1.4== | |
| + | <StructureSection load='5jr0' size='340' side='right'caption='[[5jr0]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5jr0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JR0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JR0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solid-state NMR, 10 models</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jr0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jr0 OCA], [https://pdbe.org/5jr0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jr0 RCSB], [https://www.ebi.ac.uk/pdbsum/5jr0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jr0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SCN4A_RAT SCN4A_RAT] This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. This sodium channel may be present in both denervated and innervated skeletal muscle.<ref>PMID:2559760</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Ion channels 3D structures|Ion channels 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rattus norvegicus]] | ||
| + | [[Category: Egawa A]] | ||
| + | [[Category: Fujiwara T]] | ||
| + | [[Category: Ikeda K]] | ||
| + | [[Category: Niitsu A]] | ||
| + | [[Category: Tachibana K]] | ||
Current revision
Domain 4 Segment 6 of voltage-gated sodium channel Nav1.4
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