1oy5

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[[Image:1oy5.gif|left|200px]]
 
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{{Structure
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==Crystal structure of tRNA (m1G37) methyltransferase from Aquifex aeolicus==
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|PDB= 1oy5 |SIZE=350|CAPTION= <scene name='initialview01'>1oy5</scene>, resolution 2.60&Aring;
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<StructureSection load='1oy5' size='340' side='right'caption='[[1oy5]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1oy5]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OY5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OY5 FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine-N(1)-)-methyltransferase tRNA (guanine-N(1)-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.31 2.1.1.31] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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|GENE= TRMD OR AQ_1489 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=63363 Aquifex aeolicus])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oy5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oy5 OCA], [https://pdbe.org/1oy5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oy5 RCSB], [https://www.ebi.ac.uk/pdbsum/1oy5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oy5 ProSAT], [https://www.topsan.org/Proteins/BSGC/1oy5 TOPSAN]</span></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG0336 TrmD]</span>
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</table>
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|RELATEDENTRY=
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== Function ==
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1oy5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oy5 OCA], [http://www.ebi.ac.uk/pdbsum/1oy5 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1oy5 RCSB]</span>
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[https://www.uniprot.org/uniprot/TRMD_AQUAE TRMD_AQUAE] Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605]
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}}
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oy/1oy5_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1oy5 ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of tRNA (m1G37) methyltransferase from Aquifex aeolicus'''
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==See Also==
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*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1OY5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OY5 OCA].
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==Reference==
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Crystal structure of tRNA (m1G37) methyltransferase from Aquifex aeolicus at 2.6 A resolution: a novel methyltransferase fold., Liu J, Wang W, Shin DH, Yokota H, Kim R, Kim SH, Proteins. 2003 Nov 1;53(2):326-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14517984 14517984]
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[[Category: Aquifex aeolicus]]
[[Category: Aquifex aeolicus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: tRNA (guanine-N(1)-)-methyltransferase]]
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[[Category: Kim R]]
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[[Category: BSGC, Berkeley Structural Genomics Center.]]
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[[Category: Kim SH]]
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[[Category: Kim, R.]]
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[[Category: Liu J]]
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[[Category: Kim, S H.]]
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[[Category: Shin DH]]
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[[Category: Liu, J.]]
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[[Category: Wang W]]
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[[Category: Shin, D H.]]
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[[Category: Yokota H]]
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[[Category: Wang, W.]]
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[[Category: Yokota, H.]]
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[[Category: berkeley structural genomics center]]
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[[Category: bsgc structure funded by nih]]
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[[Category: crystal structure]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomic]]
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[[Category: trmd]]
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[[Category: trna (m1g37) methyltransferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:52:05 2008''
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Current revision

Crystal structure of tRNA (m1G37) methyltransferase from Aquifex aeolicus

PDB ID 1oy5

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