5tc3
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of IMP dehydrogenase from Ashbya gossypii bound to ATP and GDP== | |
| + | <StructureSection load='5tc3' size='340' side='right'caption='[[5tc3]], [[Resolution|resolution]] 2.46Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5tc3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Eremothecium_gossypii_ATCC_10895 Eremothecium gossypii ATCC 10895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TC3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TC3 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.462Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tc3 OCA], [https://pdbe.org/5tc3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tc3 RCSB], [https://www.ebi.ac.uk/pdbsum/5tc3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tc3 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q756Z6_ASHGO Q756Z6_ASHGO] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_03156] | ||
| - | + | ==See Also== | |
| - | + | *[[Inosine monophosphate dehydrogenase 3D structures|Inosine monophosphate dehydrogenase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Eremothecium gossypii ATCC 10895]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Buey RM]] | ||
| + | [[Category: Fernandez-Justel D]] | ||
| + | [[Category: Revuelta JL]] | ||
| + | [[Category: De Pereda JM]] | ||
Current revision
Structure of IMP dehydrogenase from Ashbya gossypii bound to ATP and GDP
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