5tch

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(New page: '''Unreleased structure''' The entry 5tch is ON HOLD Authors: Michalska, K., Maltseva, N.I., Jedrzejczak, R., Wellington. S., Nag, P.P., Fisher, S.L., Schreiber, S.L., Hung, D.T., Joach...)
Current revision (15:39, 6 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 5tch is ON HOLD
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==Crystal structure of tryptophan synthase from M. tuberculosis - ligand-free form, TrpA-G66V mutant==
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<StructureSection load='5tch' size='340' side='right'caption='[[5tch]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5tch]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TCH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TCH FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tch FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tch OCA], [https://pdbe.org/5tch PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tch RCSB], [https://www.ebi.ac.uk/pdbsum/5tch PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tch ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRPA_MYCTU TRPA_MYCTU] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
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Authors: Michalska, K., Maltseva, N.I., Jedrzejczak, R., Wellington. S., Nag, P.P., Fisher, S.L., Schreiber, S.L., Hung, D.T., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
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==See Also==
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*[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]]
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Description: Crystal structure of tryptophan synthase from M. tuberculosis -ligand-free form, TrpA-G66V mutant
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__TOC__
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[[Category: Unreleased Structures]]
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</StructureSection>
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[[Category: Wellington. S]]
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[[Category: Large Structures]]
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[[Category: Michalska, K]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Joachimiak, A]]
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[[Category: Fisher SL]]
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[[Category: Maltseva, N.I]]
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[[Category: Hung DT]]
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[[Category: Hung, D.T]]
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[[Category: Jedrzejczak R]]
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[[Category: Fisher, S.L]]
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[[Category: Joachimiak A]]
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[[Category: Jedrzejczak, R]]
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[[Category: Maltseva N]]
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[[Category: Schreiber, S.L]]
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[[Category: Michalska K]]
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[[Category: Center For Structural Genomics Of Infectious Diseases (Csgid)]]
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[[Category: Nag PP]]
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[[Category: Nag, P.P]]
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[[Category: Schreiber SL]]
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[[Category: Wellington S]]

Current revision

Crystal structure of tryptophan synthase from M. tuberculosis - ligand-free form, TrpA-G66V mutant

PDB ID 5tch

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