5jww

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==T4 Lysozyme L99A/M102Q with 1-Hydro-2-ethyl-1,2-azaborine Bound==
==T4 Lysozyme L99A/M102Q with 1-Hydro-2-ethyl-1,2-azaborine Bound==
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<StructureSection load='5jww' size='340' side='right' caption='[[5jww]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
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<StructureSection load='5jww' size='340' side='right'caption='[[5jww]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5jww]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JWW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JWW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5jww]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_T4 Escherichia phage T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JWW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JWW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6OQ:2-ETHYL-1,2-DIHYDRO-1,2-AZABORININE'>6OQ</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.47&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jwt|5jwt]], [[5jwu|5jwu]], [[5jwv|5jwv]], [[5jwx|5jwx]], [[5jws|5jws]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6OQ:2-ETHYL-1,2-DIHYDRO-1,2-AZABORININE'>6OQ</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jww FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jww OCA], [https://pdbe.org/5jww PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jww RCSB], [https://www.ebi.ac.uk/pdbsum/5jww PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jww ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jww FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jww OCA], [http://pdbe.org/5jww PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jww RCSB], [http://www.ebi.ac.uk/pdbsum/5jww PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jww ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4]] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
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[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5jww" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5jww" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Lysin 3D structures|Lysin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lysozyme]]
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[[Category: Escherichia phage T4]]
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[[Category: Fischer, M]]
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[[Category: Large Structures]]
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[[Category: Lee, H]]
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[[Category: Fischer M]]
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[[Category: Liu, S Y]]
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[[Category: Lee H]]
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[[Category: Shoichet, B K]]
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[[Category: Liu S-Y]]
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[[Category: Hydrolase]]
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[[Category: Shoichet BK]]
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[[Category: Phage lysozyme azaborine]]
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Current revision

T4 Lysozyme L99A/M102Q with 1-Hydro-2-ethyl-1,2-azaborine Bound

PDB ID 5jww

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