This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5lis
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
==Insulin solved by Native SAD from a dataset collected in one second== | ==Insulin solved by Native SAD from a dataset collected in one second== | ||
| - | <StructureSection load='5lis' size='340' side='right' caption='[[5lis]], [[Resolution|resolution]] 2.29Å' scene=''> | + | <StructureSection load='5lis' size='340' side='right'caption='[[5lis]], [[Resolution|resolution]] 2.29Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5lis]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5lis]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LIS FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.293Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lis OCA], [https://pdbe.org/5lis PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lis RCSB], [https://www.ebi.ac.uk/pdbsum/5lis PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lis ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/INS_PIG INS_PIG] Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 17: | Line 18: | ||
</div> | </div> | ||
<div class="pdbe-citations 5lis" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5lis" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Insulin 3D Structures|Insulin 3D Structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Sus scrofa]] | [[Category: Sus scrofa]] | ||
| - | [[Category: Casanas | + | [[Category: Casanas A]] |
| - | [[Category: Finke | + | [[Category: Finke A]] |
| - | [[Category: Wang | + | [[Category: Wang M]] |
| - | + | ||
| - | + | ||
Current revision
Insulin solved by Native SAD from a dataset collected in one second
| |||||||||||
