5dq0

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==Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site==
==Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site==
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<StructureSection load='5dq0' size='340' side='right' caption='[[5dq0]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='5dq0' size='340' side='right'caption='[[5dq0]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5dq0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DQ0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DQ0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5dq0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DQ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DQ0 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dq0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dq0 OCA], [http://pdbe.org/5dq0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dq0 RCSB], [http://www.ebi.ac.uk/pdbsum/5dq0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dq0 ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dq0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dq0 OCA], [https://pdbe.org/5dq0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dq0 RCSB], [https://www.ebi.ac.uk/pdbsum/5dq0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dq0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NRP2_HUMAN NRP2_HUMAN]] High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF.
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[https://www.uniprot.org/uniprot/NRP2_HUMAN NRP2_HUMAN] High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF.
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==See Also==
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*[[Neuropilin|Neuropilin]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Djordjevic, S]]
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[[Category: Homo sapiens]]
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[[Category: Rana, R R]]
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[[Category: Large Structures]]
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[[Category: Tsai, Y I]]
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[[Category: Djordjevic S]]
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[[Category: Zachary, I]]
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[[Category: Rana RR]]
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[[Category: Neuropilin]]
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[[Category: Tsai YI]]
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[[Category: Signaling protein]]
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[[Category: Zachary I]]
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[[Category: Vegf]]
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Current revision

Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site

PDB ID 5dq0

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