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5l03
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE Synthase from BURKHOLDERIA PSEUDOMALLEI bound to L-tryptophan hydroxamate== | |
| + | <StructureSection load='5l03' size='340' side='right'caption='[[5l03]], [[Resolution|resolution]] 1.47Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5l03]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L03 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5L03 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.469Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6ZB:N-hydroxy-L-tryptophanamide'>6ZB</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5l03 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l03 OCA], [https://pdbe.org/5l03 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5l03 RCSB], [https://www.ebi.ac.uk/pdbsum/5l03 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5l03 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A069B2G5_BURPE A0A069B2G5_BURPE] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).[HAMAP-Rule:MF_00107][SAAS:SAAS00731896] | ||
| - | + | ==See Also== | |
| - | + | *[[MECDP synthase 3D structures|MECDP synthase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Burkholderia pseudomallei]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Bode | + | [[Category: Blain JM]] |
| - | [[Category: | + | [[Category: Bode B]] |
| - | [[Category: | + | [[Category: Ghose D]] |
| - | [[Category: | + | [[Category: Gorman JL]] |
| - | [[Category: | + | [[Category: Goshu GM]] |
| - | [[Category: | + | [[Category: Hagen TJ]] |
| - | [[Category: | + | [[Category: Horn JR]] |
| - | [[Category: Walter | + | [[Category: Meganathan R]] |
| - | [[Category: | + | [[Category: Ranieri G]] |
| + | [[Category: Walter RL]] | ||
| + | [[Category: Zhao L]] | ||
Current revision
Crystal structure of 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE Synthase from BURKHOLDERIA PSEUDOMALLEI bound to L-tryptophan hydroxamate
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Categories: Burkholderia pseudomallei | Large Structures | Blain JM | Bode B | Ghose D | Gorman JL | Goshu GM | Hagen TJ | Horn JR | Meganathan R | Ranieri G | Walter RL | Zhao L
