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5tj5
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5tj5 is ON HOLD Authors: Mazhab-Jafari, M.T., Rohou, A., Schmidt, C., Bueler, S.A., Benlekbir, S., Robinson, C.V., Rubinstein, J.L. Description: At...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Atomic model for the membrane-embedded motor of a eukaryotic V-ATPase== | |
| + | <SX load='5tj5' size='340' side='right' viewer='molstar' caption='[[5tj5]], [[Resolution|resolution]] 3.90Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5tj5]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TJ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TJ5 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.9Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tj5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tj5 OCA], [https://pdbe.org/5tj5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tj5 RCSB], [https://www.ebi.ac.uk/pdbsum/5tj5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tj5 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/VPP1_YEAST VPP1_YEAST] Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:1491220, PubMed:8798414, PubMed:11278748). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (PubMed:1491220, PubMed:11278748). Is present only in vacuolar V-ATPase complexes; enzymes containing this subunit have a 4-fold higher ratio of proton transport to ATP hydrolysis than complexes containing the Golgi/endosomal isoform and undergo reversible dissociation of V1 and V0 in response to glucose depletion (PubMed:8798414, PubMed:11278748).<ref>PMID:11278748</ref> <ref>PMID:1491220</ref> <ref>PMID:8798414</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[ATPase 3D structures|ATPase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </SX> |
| - | [[Category: Mazhab-Jafari | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Saccharomyces cerevisiae S288C]] |
| - | [[Category: | + | [[Category: Benlekbir S]] |
| - | [[Category: | + | [[Category: Bueler SA]] |
| - | [[Category: Schmidt | + | [[Category: Mazhab-Jafari MT]] |
| + | [[Category: Robinson CV]] | ||
| + | [[Category: Rohou A]] | ||
| + | [[Category: Rubinstein JL]] | ||
| + | [[Category: Schmidt C]] | ||
Current revision
Atomic model for the membrane-embedded motor of a eukaryotic V-ATPase
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