5tj5

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'''Unreleased structure'''
 
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The entry 5tj5 is ON HOLD
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==Atomic model for the membrane-embedded motor of a eukaryotic V-ATPase==
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<SX load='5tj5' size='340' side='right' viewer='molstar' caption='[[5tj5]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5tj5]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TJ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TJ5 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tj5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tj5 OCA], [https://pdbe.org/5tj5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tj5 RCSB], [https://www.ebi.ac.uk/pdbsum/5tj5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tj5 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/VPP1_YEAST VPP1_YEAST] Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:1491220, PubMed:8798414, PubMed:11278748). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (PubMed:1491220, PubMed:11278748). Is present only in vacuolar V-ATPase complexes; enzymes containing this subunit have a 4-fold higher ratio of proton transport to ATP hydrolysis than complexes containing the Golgi/endosomal isoform and undergo reversible dissociation of V1 and V0 in response to glucose depletion (PubMed:8798414, PubMed:11278748).<ref>PMID:11278748</ref> <ref>PMID:1491220</ref> <ref>PMID:8798414</ref>
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Authors: Mazhab-Jafari, M.T., Rohou, A., Schmidt, C., Bueler, S.A., Benlekbir, S., Robinson, C.V., Rubinstein, J.L.
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==See Also==
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*[[ATPase 3D structures|ATPase 3D structures]]
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Description: Atomic model for the membrane-embedded motor of a eukaryotic V-ATPase
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== References ==
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[[Category: Unreleased Structures]]
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<references/>
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[[Category: Rubinstein, J.L]]
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__TOC__
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[[Category: Rohou, A]]
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</SX>
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[[Category: Mazhab-Jafari, M.T]]
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[[Category: Large Structures]]
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[[Category: Benlekbir, S]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Bueler, S.A]]
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[[Category: Benlekbir S]]
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[[Category: Robinson, C.V]]
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[[Category: Bueler SA]]
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[[Category: Schmidt, C]]
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[[Category: Mazhab-Jafari MT]]
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[[Category: Robinson CV]]
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[[Category: Rohou A]]
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[[Category: Rubinstein JL]]
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[[Category: Schmidt C]]

Current revision

Atomic model for the membrane-embedded motor of a eukaryotic V-ATPase

5tj5, resolution 3.90Å

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OCA

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