1pl1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:56, 17 April 2024) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1pl1.gif|left|200px]]
 
-
{{Structure
+
==Crystal structure of human glutathione transferase (GST) A1-1 in complex with a decarboxy-glutathione==
-
|PDB= 1pl1 |SIZE=350|CAPTION= <scene name='initialview01'>1pl1</scene>, resolution 1.75&Aring;
+
<StructureSection load='1pl1' size='340' side='right'caption='[[1pl1]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=ABY:N-(4-AMINOBUTANOYL)-S-(4-METHOXYBENZYL)-L-CYSTEINYLGLYCINE'>ABY</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>
+
<table><tr><td colspan='2'>[[1pl1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PL1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PL1 FirstGlance]. <br>
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
-
|GENE=
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ABY:N-(4-AMINOBUTANOYL)-S-(4-METHOXYBENZYL)-L-CYSTEINYLGLYCINE'>ABY</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
-
|DOMAIN=
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pl1 OCA], [https://pdbe.org/1pl1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pl1 RCSB], [https://www.ebi.ac.uk/pdbsum/1pl1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pl1 ProSAT]</span></td></tr>
-
|RELATEDENTRY=[[1pkw|1PKW]], [[1pkz|1PKZ]], [[1pl2|1PL2]]
+
</table>
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pl1 OCA], [http://www.ebi.ac.uk/pdbsum/1pl1 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1pl1 RCSB]</span>
+
== Function ==
-
}}
+
[https://www.uniprot.org/uniprot/GSTA1_HUMAN GSTA1_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.<ref>PMID:20606271</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pl/1pl1_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pl1 ConSurf].
 +
<div style="clear:both"></div>
-
'''Crystal structure of human glutathione transferase (GST) A1-1 in complex with a decarboxy-glutathione'''
+
==See Also==
-
 
+
*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
-
 
+
== References ==
-
==About this Structure==
+
<references/>
-
1PL1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PL1 OCA].
+
__TOC__
-
[[Category: Glutathione transferase]]
+
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Grahn, E.]]
+
[[Category: Grahn E]]
-
[[Category: Grehn, L.]]
+
[[Category: Grehn L]]
-
[[Category: Gustafsson, A.]]
+
[[Category: Gustafsson A]]
-
[[Category: Jakobsson, E.]]
+
[[Category: Jakobsson E]]
-
[[Category: Kleywegt, G J.]]
+
[[Category: Kleywegt GJ]]
-
[[Category: Madsen, D.]]
+
[[Category: Madsen D]]
-
[[Category: Mannervik, B.]]
+
[[Category: Mannervik B]]
-
[[Category: Olin, B.]]
+
[[Category: Olin B]]
-
[[Category: Wahlberg, M.]]
+
[[Category: Wahlberg M]]
-
[[Category: domain1:alpha-beta]]
+
-
[[Category: domain2:alpha-helical]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:01:08 2008''
+

Current revision

Crystal structure of human glutathione transferase (GST) A1-1 in complex with a decarboxy-glutathione

PDB ID 1pl1

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1pl1"
Personal tools