4u3f

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==Cytochrome bc1 complex from chicken with designed inhibitor bound==
==Cytochrome bc1 complex from chicken with designed inhibitor bound==
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<StructureSection load='4u3f' size='340' side='right' caption='[[4u3f]], [[Resolution|resolution]] 3.23&Aring;' scene=''>
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<StructureSection load='4u3f' size='340' side='right'caption='[[4u3f]], [[Resolution|resolution]] 3.23&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4u3f]] is a 20 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U3F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U3F FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4u3f]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U3F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4U3F FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=CDL:CARDIOLIPIN'>CDL</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PEE:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE'>PEE</scene>, <scene name='pdbligand=U10:UBIQUINONE-10'>U10</scene>, <scene name='pdbligand=Y52:METHYL+(2E)-3-METHOXY-2-(2-{[(5-METHOXY-1,3-BENZOTHIAZOL-2-YL)SULFANYL]METHYL}PHENYL)PROP-2-ENOATE'>Y52</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2312&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AME:N-ACETYLMETHIONINE'>AME</scene>, <scene name='pdbligand=FME:N-FORMYLMETHIONINE'>FME</scene>, <scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AME:N-ACETYLMETHIONINE'>AME</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=CDL:CARDIOLIPIN'>CDL</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=FME:N-FORMYLMETHIONINE'>FME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PEE:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE'>PEE</scene>, <scene name='pdbligand=U10:UBIQUINONE-10'>U10</scene>, <scene name='pdbligand=Y52:METHYL+(2E)-3-METHOXY-2-(2-{[(5-METHOXY-1,3-BENZOTHIAZOL-2-YL)SULFANYL]METHYL}PHENYL)PROP-2-ENOATE'>Y52</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3tgu|3tgu]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4u3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u3f OCA], [https://pdbe.org/4u3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4u3f RCSB], [https://www.ebi.ac.uk/pdbsum/4u3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4u3f ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquinol--cytochrome-c_reductase Ubiquinol--cytochrome-c reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.2.2 1.10.2.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u3f OCA], [http://pdbe.org/4u3f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4u3f RCSB], [http://www.ebi.ac.uk/pdbsum/4u3f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4u3f ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/D0VX30_CHICK D0VX30_CHICK]] Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain (By similarity).[PIRNR:PIRNR000022] [[http://www.uniprot.org/uniprot/CYB_CHICK CYB_CHICK]] Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity). [[http://www.uniprot.org/uniprot/UCRI_CHICK UCRI_CHICK]] Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity). [[http://www.uniprot.org/uniprot/D0VX28_CHICK D0VX28_CHICK]] This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.[PIRNR:PIRNR000019]
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[https://www.uniprot.org/uniprot/F1NAC6_CHICK F1NAC6_CHICK]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Ubiquinol--cytochrome-c reductase]]
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[[Category: Large Structures]]
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[[Category: Berry, E A]]
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[[Category: Berry EA]]
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[[Category: Huang, L S]]
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[[Category: Huang L-S]]
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[[Category: Yang, G F]]
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[[Category: Yang GF]]
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[[Category: Zhu, X L]]
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[[Category: Zhu X-L]]
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[[Category: 2fe-2]]
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[[Category: Azoxystrobin]]
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[[Category: Complex iii]]
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[[Category: Cytochrome b]]
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[[Category: Cytochrome bc1]]
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[[Category: Cytochrome c1]]
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[[Category: Electron transport]]
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[[Category: Heme]]
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[[Category: Heme protein]]
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[[Category: Inner membrane]]
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[[Category: Iron]]
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[[Category: Iron-sulfur]]
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[[Category: Membrane binding]]
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[[Category: Membrane protein]]
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[[Category: Metal-binding]]
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[[Category: Mitochondrial inner membrane]]
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[[Category: Mitochondrion]]
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[[Category: Oxidoreductase]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
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[[Category: Redox enzyme respiratory chain]]
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[[Category: Respiratory chain]]
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[[Category: Rieske iron sulfur protein]]
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[[Category: Stigmatellin]]
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[[Category: Strobilurin]]
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[[Category: Transmembrane]]
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[[Category: Ubiquinone]]
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Current revision

Cytochrome bc1 complex from chicken with designed inhibitor bound

PDB ID 4u3f

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OCA

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