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1e81
From Proteopedia
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| - | [[Image:1e81.gif|left|200px]]<br /> | ||
| - | <applet load="1e81" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1e81, resolution 2.05Å" /> | ||
| - | '''ENDOTHIAPEPSIN COMPLEX WITH RENIN INHIBITOR MERCK-KGAA-EMD61395'''<br /> | ||
| - | == | + | ==Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD61395== |
| - | + | <StructureSection load='1e81' size='340' side='right'caption='[[1e81]], [[Resolution|resolution]] 2.05Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1e81]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E81 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E81 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=M91:(2S)-1-{[(2R)-1-{[(2S,3S)-1-CYCLOHEXYL-3-HYDROXY-4-(2-OXOPYRIDIN-1(2H)-YL)BUTAN-2-YL]AMINO}-3-(METHYLSULFANYL)-1-OXOPROPAN-2-YL]AMINO}-1-OXO-3-PHENYLPROPAN-2-YL+4-AMINOPIPERIDINE-1-CARBOXYLATE'>M91</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e81 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e81 OCA], [https://pdbe.org/1e81 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e81 RCSB], [https://www.ebi.ac.uk/pdbsum/1e81 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e81 ProSAT]</span></td></tr> | |
| - | [ | + | </table> |
| - | [[ | + | == Function == |
| - | [ | + | [https://www.uniprot.org/uniprot/CARP_CRYPA CARP_CRYPA] |
| - | [[ | + | == Evolutionary Conservation == |
| - | [ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e8/1e81_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e81 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| + | *[[Pepsin|Pepsin]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Cryphonectria parasitica]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Cooper JB]] | ||
| + | [[Category: Raddatz P]] | ||
| + | [[Category: Read JA]] | ||
| + | [[Category: Rippmann F]] | ||
| + | [[Category: Toldo L]] | ||
Current revision
Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD61395
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