5h1e
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Interaction between vitamin D receptor and coactivator peptide SRC2-3== | |
| + | <StructureSection load='5h1e' size='340' side='right'caption='[[5h1e]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5h1e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H1E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5H1E FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=VDX:5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL'>VDX</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5h1e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5h1e OCA], [https://pdbe.org/5h1e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5h1e RCSB], [https://www.ebi.ac.uk/pdbsum/5h1e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5h1e ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/VDR_RAT VDR_RAT] Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.<ref>PMID:17227670</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Vitamin D receptor 3D structures|Vitamin D receptor 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Itoh | + | [[Category: Rattus norvegicus]] |
| - | [[Category: Kato | + | [[Category: Anami Y]] |
| + | [[Category: Egawa D]] | ||
| + | [[Category: Itoh T]] | ||
| + | [[Category: Kataoka S]] | ||
| + | [[Category: Kato A]] | ||
| + | [[Category: Yamamoto K]] | ||
Current revision
Interaction between vitamin D receptor and coactivator peptide SRC2-3
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Categories: Homo sapiens | Large Structures | Rattus norvegicus | Anami Y | Egawa D | Itoh T | Kataoka S | Kato A | Yamamoto K
