This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5t3t

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:54, 4 October 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Ebola virus VP30 CTD bound to nucleoprotein==
==Ebola virus VP30 CTD bound to nucleoprotein==
-
<StructureSection load='5t3t' size='340' side='right' caption='[[5t3t]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
+
<StructureSection load='5t3t' size='340' side='right'caption='[[5t3t]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5t3t]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T3T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T3T FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5t3t]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Ebola_virus_-_Mayinga,_Zaire,_1976 Ebola virus - Mayinga, Zaire, 1976]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T3T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5T3T FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5t3w|5t3w]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t3t OCA], [http://pdbe.org/5t3t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t3t RCSB], [http://www.ebi.ac.uk/pdbsum/5t3t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t3t ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5t3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t3t OCA], [https://pdbe.org/5t3t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5t3t RCSB], [https://www.ebi.ac.uk/pdbsum/5t3t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5t3t ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/NCAP_EBOZM NCAP_EBOZM]] Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication. During replication, encapsidation by NP is coupled to RNA synthesis and all replicative products are resistant to nucleases.
+
[https://www.uniprot.org/uniprot/VP30_EBOZM VP30_EBOZM] Acts as a transcription anti-termination factor immediately after transcription initiation, but does not affect transcription elongation. This function has been found to be dependent on the formation of an RNA stem-loop at the transcription start site of the first gene. Binds to RNA.<ref>PMID:12163572</ref> [https://www.uniprot.org/uniprot/NCAP_EBOZM NCAP_EBOZM] Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication. During replication, encapsidation by NP is coupled to RNA synthesis and all replicative products are resistant to nucleases.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 23: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Abelson, D M]]
+
[[Category: Ebola virus - Mayinga, Zaire, 1976]]
-
[[Category: Kirchdoerfer, R N]]
+
[[Category: Large Structures]]
-
[[Category: Moyer, C L]]
+
[[Category: Abelson DM]]
-
[[Category: Saphire, E O]]
+
[[Category: Kirchdoerfer RN]]
-
[[Category: Co-factor]]
+
[[Category: Moyer CL]]
-
[[Category: Regulator]]
+
[[Category: Saphire EO]]
-
[[Category: Replication]]
+
-
[[Category: Transcription]]
+
-
[[Category: Viral protein]]
+

Current revision

Ebola virus VP30 CTD bound to nucleoprotein

PDB ID 5t3t

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5t3t"
Personal tools