5eid

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==AKR2A ankyrin repeat domain==
==AKR2A ankyrin repeat domain==
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<StructureSection load='5eid' size='340' side='right' caption='[[5eid]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='5eid' size='340' side='right'caption='[[5eid]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5eid]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EID OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EID FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5eid]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EID OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EID FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eid OCA], [http://pdbe.org/5eid PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eid RCSB], [http://www.ebi.ac.uk/pdbsum/5eid PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eid ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5eid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eid OCA], [https://pdbe.org/5eid PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5eid RCSB], [https://www.ebi.ac.uk/pdbsum/5eid PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5eid ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/AKR2_ARATH AKR2_ARATH]] Seems to be involved in the regulation of hydrogen peroxide levels during biotic and abiotic stresses by optimizing the ascorbate peroxidase 3 (APX3) hydrogen peroxide-degrading activity. This regulation might be monitored by GRF6.
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[https://www.uniprot.org/uniprot/AKR2A_ARATH AKR2A_ARATH] Exhibits chaperone activity toward chloroplast outer envelope membrane, mitochondrion outer membrane, endoplasmic reticulum membrane and peroxisomal proteins, by recruiting specific proteins containing a single transmembrane associated with an AKR2A-binding sequence (ABS) and subsequently binding glycolipids (e.g. monogalactosyldiacylglycerol (MGDG) and phosphatidylglycerol (PG)) present in the membrane of the target organelle (PubMed:18193034, PubMed:20215589, PubMed:25203210). Seems to be involved in the regulation of hydrogen peroxide levels during biotic and abiotic stresses by optimizing the ascorbate peroxidase 3 (APX3) hydrogen peroxide-degrading activity. This regulation might be monitored by GRF6. Cytosolic targeting factor for chloroplast outer membrane (COM) proteins that mediates sorting and targeting of nascent chloroplast outer envelope membrane (OEM) proteins to the chloroplast. Facilitates the targeting of OEP7 to chloroplasts (PubMed:18193034). Facilitates the targeting of APX3 to peroxisomes. Involved in cellular metabolism (e.g. peroxisome activity) and required for plant growth and development (PubMed:20215589).<ref>PMID:11862948</ref> <ref>PMID:18193034</ref> <ref>PMID:20215589</ref> <ref>PMID:25203210</ref>
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==See Also==
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*[[Ankyrin repeat domain-containing protein 3D structures|Ankyrin repeat domain-containing protein 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Li, H]]
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[[Category: Arabidopsis thaliana]]
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[[Category: Pu, H]]
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[[Category: Large Structures]]
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[[Category: Akr2a]]
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[[Category: Li H]]
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[[Category: Ankyrin repeat domain]]
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[[Category: Pu H]]
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[[Category: Cytosolic targeting factor]]
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[[Category: Protein transport]]
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AKR2A ankyrin repeat domain

PDB ID 5eid

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