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Maltose-binding protein

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== Structural highlights ==
== Structural highlights ==
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The <scene name='47/471830/Cv/4'>MBP sugar binding cleft is rich with protein-ligand hydrogen bonds</scene><ref>PMID:9309217</ref>. Water molecules shown as red spheres.
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The <scene name='47/471830/Cv/5'>MBP sugar binding cleft is rich with protein-ligand hydrogen bonds</scene><ref>PMID:9309217</ref>. Water molecules are shown as red spheres.
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</StructureSection>
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==3D structures of maltose-binding protein==
==3D structures of maltose-binding protein==
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[[Maltose-binding protein 3D structures]]
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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</StructureSection>
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{{#tree:id=OrganizedByTopic|openlevels=0|
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*'''MBP'''
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**[[1llx]], [[1jw4]], [[1lls]], [[1omp]] - MBP<br />
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**[[3sey]], [[3sex]], [[3sew]], [[3sev]], [[3seu]], [[3set]], [[3ses]], [[3ser]], [[2v93]], [[1zkb]], [[1n3x]], [[1peb ]], [[1mpc]], [[3kjt]], [[1mdp]], [[1mdq]] - MBP (mutant)<br />
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**[[2klf]], [[2d21]] – MBP – NMR<br />
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**[[1ziu]] – MBP (mutant) + Ni<br />
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**[[1zjl]] – MBP (mutant) + Zn<br />
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**[[1zmg]] - MBP (mutant) + Cu<br />
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**[[4log]] - MBP /nuclear receptor<br />
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**[[4ogm]] - MBP /pilin<br />
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**[[4pe2]] - MBP /pilA1<br />
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**[[4khz]] - MBP MalK, MalF, MalG, MBP <br />
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**[[3fh6]] - MBP MalK, MalF, MalG <br />
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**[[2xd2]] – SpMBP – ''Streptococcus pneumoniae''
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*MBP complex with saccharide
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**[[1n3w]], [[1nl5]], [[1mpd]], [[1iud]], [[1jvx]], [[1jvy]] - MBP (mutant) + maltose<br />
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**[[1anf]], [[1jw5]], [[2xz3]] - MBP + maltose<br />
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**[[3mbp]] - MBP + maltotriose<br />
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**[[4mbp]] - MBP + maltotetrose<br />
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**[[1ez9]] - MBP + maltodextrin<br />
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**[[3hpi]] – MBP (mutant) + sucrose<br />
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**[[1lax]] - MBP (mutant) + glucose<br />
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**[[2h25]], [[1ezo]], [[1dmb]] - MBP + β-cyclodextrin<br />
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**[[1ezp]] - MBP (mutant) + β-cyclodextrin<br />
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**[[1fqa]], [[1fqb]], [[1fqc]], [[1fqd]] - MBP + maltotetraitol<br />
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**[[3puy]], [[3puz]] - MBP MalK, MalF, MalG, MBP + maltose + AMPPNP<br />
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**[[3rlf]] - MBP MalK, MalF, MalG, MBP + maltose + AMPPNP<br />
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**[[4jbw]] - MBP MalK, MalF, MalG + EIIAGLC<br />
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**[[3pv0]] - MBP MalK, MalF, MalG, MBP + maltose <br />
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**[[2r6g]], [[3puv]], [[3puw]], [[3pux]], [[4ki0]] - MBP MalK, MalF, MalG, MBP + maltose + nucleotide<br />
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**[[3ob4]] - MBP AraH2 (mutant) + maltotriose<br />
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**[[1elj]] – MBP + glucose – ''Pyrococcus furiosus''<br />
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**[[3jyr]] – MBP + α-acarbose – ''Salmonella enterica''<br />
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**[[2xd3]] – SpMBP + maltopentaose
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*MBP complex with protein
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**[[3pgf]] – MBP (mutant) + synthetic antigen binder<br />
 
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**[[2r6g]], [[4khz]], [[4ki0]] - MBP + maltose transporter complex<br />
 
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**[[3puv]], [[3puw]], [[3pux]] – MBP + maltose transporter complex + ADP <br />
 
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**[[3rlf]] - MBP + maltose transporter complex + Mg-AMPPNP<br />
 
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**[[1svx]] – MBP + ankyrin repeat protein OFF7<br />
 
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**[[1nmu]] - MBP + ribosomal protein L30<br />
 
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**[[1t0k]] - MBP + ribosomal protein L30 + RNA<br />
 
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**[[3rum]] – MBP + ristocetin<br />
 
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**[[4nuf]] - MBP /nuclear receptor + orphan nuclear receptor peptide<br />
 
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}}
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

E. coli maltose-binding protein complex with maltose (PDB entry 1anf)

Drag the structure with the mouse to rotate

References

  1. ↑ Kapust RB, Waugh DS. Escherichia coli maltose-binding protein is uncommonly effective at promoting the solubility of polypeptides to which it is fused. Protein Sci. 1999 Aug;8(8):1668-74. PMID:10452611 doi:http://dx.doi.org/10.1110/ps.8.8.1668
  2. ↑ Sun P, Tropea JE, Waugh DS. Enhancing the solubility of recombinant proteins in Escherichia coli by using hexahistidine-tagged maltose-binding protein as a fusion partner. Methods Mol Biol. 2011;705:259-74. doi: 10.1007/978-1-61737-967-3_16. PMID:21125392 doi:http://dx.doi.org/10.1007/978-1-61737-967-3_16
  3. ↑ Quiocho FA, Spurlino JC, Rodseth LE. Extensive features of tight oligosaccharide binding revealed in high-resolution structures of the maltodextrin transport/chemosensory receptor. Structure. 1997 Aug 15;5(8):997-1015. PMID:9309217

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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