5h7t
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==A GH19 chitinase domain from the Cryptomeria japnonica pollen (CJP-4) allergen== | |
| + | <StructureSection load='5h7t' size='340' side='right'caption='[[5h7t]], [[Resolution|resolution]] 1.19Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5h7t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptomeria_japonica Cryptomeria japonica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H7T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5H7T FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.19Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5h7t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5h7t OCA], [https://pdbe.org/5h7t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5h7t RCSB], [https://www.ebi.ac.uk/pdbsum/5h7t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5h7t ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CHI4_CRYJA CHI4_CRYJA] Has endochitinase activity (PubMed:15725197). Hydrolyzes chitin oligosaccharides, GlcNAc(n), with different degrees of polymerization (n=2-6), a soluble substrate glycol chitin, and an insoluble substrate beta-chitin nanofiber in vitro. GlcNAc(6) is hydrolyzed at the second glycosidic linkage from the reducing end in addition to the middle linkage. GlcNAc(4) is further hydrolyzed to GlcNAc(2). Has antifungal activity against hyphal growth of H.rufa (PubMed:29756783).<ref>PMID:15725197</ref> <ref>PMID:29756783</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Chitinase 3D structures|Chitinase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Cryptomeria japonica]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fukamizo T]] | ||
| + | [[Category: Numata T]] | ||
| + | [[Category: Ohnuma T]] | ||
| + | [[Category: Takashima T]] | ||
| + | [[Category: Umemoto N]] | ||
Current revision
A GH19 chitinase domain from the Cryptomeria japnonica pollen (CJP-4) allergen
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