5mbm
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5mbm is ON HOLD Authors: Turk, D., Kramer, L., Renko, M., Turk, B. Description: Cathepsin B in complex with DARPin 8h6 [[Category: Unreleased Struc...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Cathepsin B in complex with DARPin 8h6== | |
| + | <StructureSection load='5mbm' size='340' side='right'caption='[[5mbm]], [[Resolution|resolution]] 2.76Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5mbm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MBM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MBM FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.76Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SCH:S-METHYL-THIO-CYSTEINE'>SCH</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mbm OCA], [https://pdbe.org/5mbm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mbm RCSB], [https://www.ebi.ac.uk/pdbsum/5mbm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mbm ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CATB_HUMAN CATB_HUMAN] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. | ||
| - | + | ==See Also== | |
| - | + | *[[Cathepsin 3D structures|Cathepsin 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Kramer | + | [[Category: Synthetic construct]] |
| - | [[Category: Turk | + | [[Category: Kramer L]] |
| + | [[Category: Renko M]] | ||
| + | [[Category: Turk B]] | ||
| + | [[Category: Turk D]] | ||
Current revision
Cathepsin B in complex with DARPin 8h6
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